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Doctor's Best   High Absorption Magnesium 100 mg - 120 Tablets

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Item Number: DRB1120
Serving Size: 2 Tablets Servings per Container: 60
Price per Serving:  $0.20 Price per Unit*: $0.10 per Tablet
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Regular Price:  $17.49 $11.70
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For science-based nutrition in a dietary supplement that supports the heart‚ nervous system‚ and cellular energy production‚ try Doctor’s Best’s High Absorption 100% Chelated Magnesium. Each tablet provides elemental magnesium‚ which has been chelated with the amino acids glycine and lysine. As an essential mineral‚ magnesium plays many important roles. It helps cells produce metabolic energy‚ supports optimum nerve function and healthy bones‚ promotes muscle relaxation‚ and helps you maintain a healthy heartbeat.

Glycine has been shown to be an efficient carrier for minerals by facilitating absorption in the intestinal tract. It’s used by the body to form collagen‚ a key protein in cartilage and connective tissue; this may ward off joint pain and stiffness. Meanwhile‚ lysine is an essential amino acid that assists gastric functioning.

Magnesium acts a co-factor for metabolic enzymes. Perhaps most importantly‚ it works very closely with calcium to promote tooth and bone density. Weak bones can interfere with your everyday life by making you more susceptible to injuries caused by motion.

Magnesium – Important for Everyone‚ Deficient in Many

Loss of magnesium during food processing and low magnesium content in common processed foods are factors in a lack of magnesium. In addition‚ absorption of the mineral tends to decrease with age. The elderly may be susceptible to magnesium deficiency for a variety of reasons‚ including inadequate intake‚ poor absorption due to impaired gastrointestinal function‚ and the use of drugs such as diuretics that deplete magnesium stores from the body. A lack of magnesium may cause the visible signs of aging to appear more quickly‚ due to its impact on the cardiovascular and nervous systems‚ as well as on muscles and the kidneys. Women who take both synthetic estrogen and calcium supplements may be at risk for low blood levels of magnesium. Estrogen promotes the transfer of magnesium from blood to soft tissues; low blood magnesium may result if the ratio of calcium to magnesium intake exceeds 4 to 1. Magnesium supplementation is thus advisable for women taking these supplements. Unfortunately‚ a low magnesium status may often not be recognized‚ and many people of all ages who could benefit from supplementation go without it.

Magnesium – The Versatile Mineral

The average adult body contains anywhere from about 21 to 28 grams of magnesium. Approximately 60 percent of the body’s magnesium supply is stored in bone. Soft tissue‚ such as skeletal muscle‚ contains 38%‚ leaving only about 1–2% of the total body magnesium content in blood plasma and red blood cells.

Magnesium works as a co-factor for over 300 enzymatic reactions in the body. Metabolism uses a phosphate-containing molecule called ATP as its energy source. Magnesium is required for all reactions involving ATP. ATP supplies the energy for physical activity by releasing energy stored in phosphate bonds. Skeletal and heart muscle use up large amounts of ATP. The energy for muscle contraction is released when one of ATP’s phosphate bonds is broken‚ in a reaction that produces ADP. Phosphate is added back to ADP‚ re-forming ATP. ATP also powers the cellular calcium pump‚ which allows muscle cells to relax. Because it participates in these ATP-controlled processes‚ magnesium is vitally important for muscle contraction and relaxation. By controlling the flow of sodium‚ potassium and calcium in and out of cells‚ magnesium regulates the function of nerves as well as muscles.

The heart is the only muscle in the body that generates its own electrical impulses. Through its influence on the heart’s electrical conduction system‚ magnesium is essential for maintenance of a smooth‚ regular heartbeat. Magnesium may help your body cope with stress and increase the amount of antioxidants in your bloodstream.

Magnesium intake is tied to skeletal bone health through several pathways. Under normal physiologic conditions‚ parathyroid hormone (PTH) secretion is low when magnesium intake is not adequate. Additionally‚ PTH resistance can develop. Adequate magnesium intake can support the normal function of PTH. Low magnesium intake is further associated with a disturbance in blood levels of the active metabolite of vitamin D‚ as well as an increase in cytokines‚ both of which may impact bone health.

Numerous studies‚ large and small‚ have examined the relationship between magnesium and bone health. The dietary intakes of magnesium‚ potassium‚ fruits and vegetables are associated with increased bone density in the elderly. Research also suggests that magnesium may help support bone mineral density in women across the age spectrum.

Maximizing Absorption: Chelated Minerals Explained

Mineral absorption occurs mainly in the small intestine. Like any mineral‚ magnesium may be absorbed as an ion‚ a mineral in its elemental state that carries an electric charge. Mineral ions cross the intestinal membrane either by simple diffusion or through active transport by a protein carrier embedded in the cells lining the membrane inner wall. The magnesium in mineral salts is absorbed in ionic form. However‚ absorption of ionic minerals can be compromised by any number of factors‚ including low solubility of the starting salt (which inhibits release of the mineral ion) and the binding of the released ion to naturally occurring dietary factors such as other minerals‚ phytates‚ and fats (which form indigestible mineral complexes).

A second absorption mechanism has been discovered for minerals. Experiments have shown that minerals chemically bonded to amino acids (building blocks of protein) are absorbed differently from mineral ions. This has given rise to the introduction of "chelated" minerals as dietary supplements. Mineral amino acid chelates consist of a single atom of elemental mineral that is surrounded by two or more amino acid molecules in a stable‚ ring-like structure.

Unlike mineral salts‚ which must be digested by stomach acid before the desired mineral portion can be released and absorbed‚ mineral chelates are not broken down in the stomach or intestines. Instead‚ chelates cross the intestinal wall intact‚ carrying the mineral tightly bound and hidden within the amino acid ring. The mineral is then released into the bloodstream for use by the body.

In order for a mineral supplement to qualify as a genuine chelate‚ it must be carefully processed to ensure the mineral is chemically bonded to the amino acids in a stable molecule with the right characteristics. The magnesium glycinate/lysinate in High Absorption 100% Chelated Magnesium is a genuine dipeptide chelate. It has a molecular weight of 324 Daltons‚ considerably lower than the upper limit of 800 Daltons stated in the definition of "mineral amino acid chelates" adopted by the National Nutritional Foods Association (now known as the Natural Products Association) in 1996.

Each bottle of High Absorption by Doctor’s Best contains 120 tablets.

For over two decades‚ Doctor's Best has provided a wide variety of nutritional supplements. All Doctor's Best products are made with the highest-quality raw ingredients available on the market. Its formulations are science-based and tested for effectiveness and safety.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # DRB-00025
  • UPC # 753950000254
Official Website:

Serving Size: 2 Tablets
Servings Per Container: 60

Amount Per Serving / %Daily Value

Magnesium (elemental) 200 mg / 50%
(from 2‚000 mg magnesium lysinate glycinate chelate)

*Daily Values Not Established.

Other ingredients: Microcrystalline cellulose‚ croscarmellose sodium‚ magnesium stearate (vegetable source)‚ stearic acid‚ hypromellose and hydroxypropyl cellulose (coating).

Non-GMO / Gluten Free / Soy Free / Vegan

Take 2 tablets twice daily‚ or as recommended by a nutritionally-informed physician.

Consult a healthcare professional before use.

Store in a cool‚ dry place.

  • Dairy Free
  • Gluten Free
  • GMO Free
  • Soy Free
  • Vegan
  • Vegetarian

Ratings and Reviews

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  • 4.7
5 113
  • 113 Reviews
    • Verified Buyer


      from NY on 6/01/2022
      Havent taken these for too long yet so not sure how much its doing but im hopeful


      I like that it helps make me tired and "possibly" helps with depression


      they are pretty big but i dont have much trouble
      review-checkI would recommend this item to a friend.
    • Best Price I've Found

      from Franklin, KY on 5/20/2022
      Just started taking so I haven't seen anything I can directly relate to product.
      review-checkI would recommend this item to a friend.
    • Great product!

      from NC on 4/22/2022
      I have taken this for a while. It really helps with my restlessness at night.
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Good product

      from Rego Park NY on 3/29/2022
      High absorption.
      review-checkI would recommend this item to a friend.
    • Great product

      from Tennessee on 3/23/2022
      I have a kidney disorder and it's the only magnesium that keeps my levels in the normal range 9 tablets a day.


      It works


      review-checkI would recommend this item to a friend.
    • Works Fairly Well

      from Michigan on 3/05/2022
      I read that most people lack Magnesium and it can help you sleep, so I have been taking this product for quite a while. I think it helps me sleep better than when I don't take this supplement.
      review-checkI would recommend this item to a friend.
    • Doctor's Best High Absorption Magnesium

      from Michigan on 10/30/2021
      Have been on this formulation for quite some time. A great product that has high absorption and doesn't have a laxative effect.


      High absorption. No laxative effect.


      The tablets are fairly large and need to be swallowed with a reasonable amount of water, one at a time.
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Great for heart health.

      from Westminster, SC on 2/28/2021
      Great for heart health.


      Great for heart health.


      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Perfect as a Sleep Aid!

      from NYC on 2/27/2021
      I stopped taking for a bit & realized my sleep was very impacted. Now that I'be begun again, I see the difference it makes.
      review-checkI would recommend this item to a friend.
    • Dr’s Choice magnesium

      from Georgia on 2/01/2021
      Ships quickly


      Prefer vitamins over another medication for diabetic neuropathy.


      review-checkI would recommend this item to a friend.
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If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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