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Kirkman   Advanced Adult Multivitamin & Mineral with 5-MTHF - 180 Capsules

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Item Number: KM1283
Serving Size: 2 Capsules Servings per Container: 90
Price per Serving:  $0.39 Price per Unit*: $0.20 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Kirkman’s new Advanced Adult Multi-Vitamin/Mineral with 5-MTHF offers the same excellent blend of nutrients that are in the original formulation except that the folic acid form in this new product is 5-Methyltetrahydrofolate (5-MTHF). In addition‚ the vitamin B-12 concentration has been increased to ensure the proper absorption rate of the 5-MTHF.

This new Advanced Adult Multi-Vitamin/Mineral with 5-MTHF was formulated to offer 5-MTHF‚ which is a more active form of folate in the body than folic acid. Most foods and dietary supplements contain folic acid‚ which is a synthetic form of vitamin B that is not biologically active in the body until it is converted to 5- Methyltetrahydrofolate (5-MTHF) and 5-Formyltetrahydrofolate (folinic acid)‚ which are the active forms found in the liver and the gut.

In order for the folic acid to be converted to these biologically active forms in the body‚ a particular enzyme must be functioning normally. This enzyme is called methyltetrahydrofolate reductase (MTHFR). If this enzyme is functioning normally your body will convert the folic acid to the active forms. If certain mutations in the MTHFR gene are present‚ however‚ the conversion may not be complete‚ resulting in unmetabolized folic acid remaining in the body and incomplete utilization of the ingested folic acid.

There are approximately 40 mutations of the MTHFR gene in the body. Certain mutations may interfere with the proper conversion of folic acid to its active forms. This can lead to methyl folate deficiency and can lead to health problems and birth defects in newborns. It is estimated that 10 to 25 percent of the population have a faulty MTHFR enzyme resulting in a 40-60 percent decreased ability to convert folic acid to its biologically active forms.

With those high percentages of the potential inadequacy of the folic acid conversion process‚ modern research is now indicating a possible change in how we supplement folic acid should be considered. Rather than relying on the body’s natural processing of the folic acid conversion process‚ supplementing with an active form of folic acid is gaining momentum‚ especially in preconception and pregnancy.

Individuals with a mutation in the 5-MTHF reductase gene may benefit from Kirkman’s new Advanced Adult Multi-Vitamin/Mineral. There are no known disadvantages of utilizing 5-MTHF as your folic acid source.

Folic acid helps the body manufacture healthy new cells. Everyone needs folic acid to survive but getting enough folic acid is especially important for women intending to get pregnant or women already expecting. Inadequate levels of folic acid before and during pregnancy may seriously affect pregnancy outcomes. Foods containing significant amounts of folic acid include leafy green vegetables‚ fruits‚ beans‚ peas and nuts. In addition‚ enriched breads and cereals are fortified with folic acid. Even with the food fortification‚ supplementation is generally required and recommended by all physicians and health professionals during the childbearing years. The suggested daily requirement is 400 mcg. for the normal population‚ and 800 mcg. for pregnant or lactating women.



These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # 0484-180
  • UPC # 812325024179
Official Website: http://www.kirkmangroup.com

Serving Size: 2 Capsules
Servings Per Container: 90

Amount Per Serving / %DV

Vitamin A (as Retinol‚ Beta-Carotene) 5000 IU 1500 mcg RAE / 166%
Vitamin C (as Ascorbic Acid‚ Magnesium Ascorbate) 350 mg / 388%
Vitamin D3 (as Cholecalciferol) 1000 IU 25 mcg / 125%
Vitamin E (as Alpha-Tocopherol)(Sunflower) 30 IU 20 mg / 133%
Vitamin B1 (as Thiamine Mononitrate) 6 mg / 500%
Vitamin B2 (as Riboflavin) 6 mg / 461%
Vitamin B3 (as Niacinamide) 20 mg NE / 125%
Vitamin B6 (as Pyridoxine HCI) 6 mg / 352%
Folate (as Calcium L-5-Methyltetrahydrofolate) (Folic Acid 400 mcg) 666 mcg DFE / 167%
Vitamin B12 (as Cyanocobalamin) 120 mcg / 5000%
Biotin 100 mcg / 333%
Vitamin B5 (as D-Calcium Pantothenate) 10 mg / 200%
Iron (from Ferrous Bisglycinate Chelate) 5 mg / 27%
Iodine (from Potassium Iodine) 150 mcg / 100%
Magnesium (from Magnesium Oxide‚ Ascorbate‚ Bisglycinate Chelate) 200 mg / 47%
Zinc (from Zinc Citrate) 27 mg / 245%
Selenium (from Selenium Glycinate Complex) 70 mcg / 127%
Manganese (from Manganese Citrate) 2 mg / 86%
Chromium (from Chromium Nicotinate Glycinate Chelate) 120 mcg / 342%
Molybdenum (from Molybdenum Glycinate) 75 mcg / 166%
Kirkman® Proprietary Blend: 50 mg / *
(Coenzyme Q10‚ Resveratrol)

*Daily Value not established.

Other Ingredients: Vegetarian Capsules (hypromellose and water)‚ Magnesium Stearate (plant based)

Free of: Milk‚ eggs‚ fish‚ shellfish‚ tree nuts‚ peanuts‚ wheat and soy.

GMP certified / Hypoallergenic / Gluten-Free


Take two capsules or as directed by a physician.


Important: Store in a cool dry place and tightly capped.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose‚ call a doctor or poison control center immediately.

Caution: Formulated for adults. For children‚ consult a physician.


  • Egg Free
  • Fish Free
  • GMP (Good Manufacturing Practices) Certification
  • Nut Free
  • Peanut Free
  • Soy Free
  • Wheat Free
  • Crustacean Shellfish Free

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If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008

If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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