Thorne   5-MTHF 5 mg - 60 Capsules

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Item Number: TR1337
Serving Size: 1 Capsule Servings per Container: 60
Price per Serving:  $0.97 Price per Unit*: $0.97 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Active folate supplementation for mood‚ heart health‚ fetal development and nerve support*

5-MTHF is an active‚ tissue-ready form of folate. It's an essential B vitamin that supports methylation. Many individuals don't get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic makeup.

Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate)‚ the active form of folic acid‚ because they have intestinal or liver dysfunction‚ or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects‚ which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin‚ melatonin‚ dopamine‚ epinephrine‚ and norepinephrine‚ supplementation supports healthy mood.

Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner.

It is important for a woman of childbearing age to get enough folic acid – not just those women who are planning to become pregnant. Because half of pregnancies are unplanned‚ any woman who could become pregnant should get enough folic acid every day. Folic acid intake is especially important before conception and during early pregnancy‚ since its biggest need is during the first trimester – when a woman might not even know she is pregnant. Supplementation with the active form of folic acid – 5-MTHF (L-5 Methyltetrahydrofolate)– is always preferable.

Acting with vitamin B12‚ 5-MTHF functions as a methyl-group donor‚ thereby facilitating the conversion of the amino acid homocysteine to methionine. An elevated homocysteine level is a risk factor for a number of undesirable health conditions. Methyl-group donation is vital to many biochemical conversion processes‚ including the synthesis of serotonin‚ melatonin‚ and DNA.


These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # B132
  • UPC # 693749132011
Official Website: https://www.thorne.com

Servings Size: One Capsule
Servings Per Container: 60

One Capsule Contains: / % DV

Folate (5 mg as L-5-Methyltetrahydrofolate†) 8.3 mg DFE / 2‚075%

Daily Value (DV)

Other Ingredients: Microcrystalline Cellulose‚ Hypromellose (derived from cellulose) capsule‚ Leucine‚ Silicon Dioxide.

†This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolate (Extrafolate-S®). Extrafolate-S is a registered trademark of Gnosis S.p.A.

Gluten Free.

Take 1 capsule two to three times daily or as recommended by your health-care practitioner.

TAMPER EVIDENT: Use only if bottle is sealed. Store tightly sealed in a cool‚ dry place.

If pregnant‚ consult your health-care practitioner before using this product.

  • Egg Free
  • Gluten Free
  • High Fructose Corn Syrup Free
  • Nut Free
  • Peanut Free

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  • Question:
    Is this product equivalent to Deplin? My doctor prescribed Deplin but it is prohibitively expensive and I was hoping this might be a good alternative.
    joy Dixon on 9/30/2014 Answer:
    • Hello, thank you for contacting PureFormuals. Your health professional would be the one that would be the one that can recommend the product to you.
      Rosa on 10/01/2014

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