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Optimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian Capsules

Item # LE1234
Regular Price: $28.00Our Price: $21.00
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Optimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian Capsules
Optimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian CapsulesOptimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian CapsulesOptimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian Capsules

Product Q & A
MFG # 01439
UPC # 737870143918
Official Website: http://www.lef.org

Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine‚ folate benefits cardiovascular health and nervous system function.

Those who take ordinary folic acid supplements‚ however‚ may not be experiencing its full spectrum of effects. This is because folic acid is itself not biologically active‚ but its biological importance is due to its active form called 5-methyltetrahydrofolate (5-MTHF) after its conversion to dihydrofolic acid in the liver. Research shows that in a large proportion of the population‚ genetic dihydrofolate reductase enzyme deficiencies limited the conversion of folate to 5-MTHF‚ leaving many vulnerable to low blood 5-MTHF levels (and higher than desired homocysteine).

A more useful approach is to take the bioactive folate 5-MTHF directly‚ which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate levels compared with folic acid supplementation. 5-MTHF is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since 5-MTHF requires no conversion to be biologically active.

People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid‚ 5-MTHF is able to cross the blood-brain barrier‚ which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12)‚ vitamin B6‚ and riboflavin.

Optimized Folate now provides Quatrefolic® 5-methyltetrahydrofolate complexed with glucosamine for longer stability‚ higher water solubility and improved bioavailability compared to other forms of 5-MTHF.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Serving Size 1 vegetarian capsule
Servings Per Container 100

Amount Per Serving

Folate [as (6S)-5-Methyltetrahydrofolic acid‚ glucosamine salt]^ 1000 mcg

Other ingredients: microcrystalline cellulose‚ vegetable cellulose (capsule)‚ silica‚ vegetable stearate.

This product contains NO milk‚ egg‚ fish‚ peanuts‚ crustacean shellfish (lobster‚ crab‚ shrimp)‚ soybeans‚ tree nuts‚ wheat‚ yeast‚ gluten‚ corn‚ or rice. Contains NO sugar‚ and no artificial sweeteners‚ flavors‚ colors‚ or preservatives.

Take one capsule daily with food‚ or as recommended by a healthcare practitioner.

Do not exceed recommended dose.

When using nutritional supplements‚ please consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Optimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian Capsules
5 Stars based on 7 Review(s)
United States
5/5 Stars
I would recommend this item to a friend.

Excellent product! High quality!
February 12, 2014
Excellent product! High quality!

East Hampton, CT
5/5 Stars
I would recommend this item to a friend.

Health Benefit
December 8, 2013
Was unable to process folic acid and after researching a natural alternative to folast I purchased this product. I have been very pleased with the results.l

savannah, ga
5/5 Stars
I would recommend this item to a friend.

Helps with depression.
December 3, 2013
I notice when I run out of this product that I start getting depressed again. I take about 7 of them a day. One of the latest antidepressants on the market is a concentrated dose of this same form of B vitamin so I figured I would take a high dose and it works.

5/5 Stars
I would recommend this item to a friend.

Good product
July 6, 2013
Optimized Folate is just what my son's doctor wanted him to take.
Good price

Aallen Texas
5/5 Stars
I would recommend this item to a friend.

My doctor recommended I take this!
June 6, 2013
My doctor recommended that I take Optimized Folate & gave me a prescription for it, which when I went to pick it up at the pharmacy. They said my insurance would not pay for it & it was going to cost $148.00! I asked why, the pharmacist said it was because it was a vitamin! So he told me what was in & I found it here on Pureformulas! I guess the doctors have realized the value of vitamins! Especially this one!

Leesburg, VA
5/5 Stars
I would recommend this item to a friend.

Really happy with this brand
January 9, 2013
I really like the Life Extension brand, but I only take just the Optimized Folate. My doctor said I should take this to keep my B-6 levels up, and it works! And it has no fillers, yeast, soy, sugar, or glutens to cause nasty side effects. It's also non-prescription, and that's such a relief, as so much of my regimen is. My only complaint is that it always runs at least 20.00; and because I need to take 3 a day, one bottle only lasts a month. It would be nice to see it sold in larger quantities, instead of having to buy several bottles.
Pure - no fillerrs, yeasts, dyes, sugars, glutens, or soy products Does what it's supposed to Non-prescription No side effects
Would like to see larger quantities/bottle Slightly lowered cost would be nice; or discount +1 bottles at a time

North Carolina
5/5 Stars
I would recommend this item to a friend.

MTHR Problem
December 6, 2012
Both my daughter and I have a gene mutation where we do not metholize folate properly. Our doctor has us on Optimized Folate (L-Methylfolate) 1000 mcg.

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