Optimized Folate (L-Methylfolate) 1000 mcg 100 Vegetarian Capsules
Item # LE1234
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Product Q & A
|MFG # 1439|
UPC # 737870143918
Official Website: http://www.lef.org
Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine, folate benefits cardiovascular health and nervous system function.
Those who take ordinary folic acid supplements, however, may not be experiencing its full spectrum of effects. This is because folic acid is itself not biologically active, but its biological importance is due to its active form called 5-methyltetrahydrofolate (5-MTHF) after its conversion to dihydrofolic acid in the liver. Research shows that in a large proportion of the population, genetic dihydrofolate reductase enzyme deficiencies limited the conversion of folate to 5-MTHF, leaving many vulnerable to low blood 5-MTHF levels (and higher than desired homocysteine).
A more useful approach is to take the bioactive folate 5-MTHF directly, which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate levels compared with folic acid supplementation. 5-MTHF is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since 5-MTHF requires no conversion to be biologically active.
People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.
Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12), vitamin B6, and riboflavin.
Optimized Folate now provides Quatrefolic® 5-methyltetrahydrofolate complexed with glucosamine for longer stability, higher water solubility and improved bioavailability compared to other forms of 5-MTHF.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
|Serving Size 1 vegetarian capsule|
Servings Per Container 100
Amount Per Serving
Folate [as (6S)-5-Methyltetrahydrofolic acid, glucosamine salt]^ 1000 mcg
Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Allergy Information - Product Details
- No Artificial Colors
- Corn Free
- Egg Free
- No Artificial Flavors
- Gluten Free
- Nuts Free
- Preservatives Free
- Soy Free
- Sugar Free
- Wheat Free
- Yeast Free
|Take one capsule daily with food, or as recommended by a healthcare practitioner.|
|Do not exceed recommended dose.|
When using nutritional supplements, please consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
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