- MFG # DRB-00356
- UPC # 753950003569
The superior form of Vitamin K for Healthy Bones and Soft Tissue!
Natural Vitamin K2 – MenaQ7® contains pure MenaQ7®‚ the superior form of vitamin K for optimum bioavailability and delivery to the body. MenaQ7® is purified from natto‚ a traditional Japanese breakfast food made of fermented soybeans that is naturally rich in vitamin K2. Not just a single vitamin‚ Vitamin K is a family of fat-soluble vitamins with similar structures‚ but different metabolic properties. Vitamin K2 belongs to the group of vitamin K compounds called “menaquinones” which demonstrate greater bioactivity when compared to vitamin K1 (the ordinary form of supplemental vitamin K). Vitamin K2 is absorbed more completely‚ remains in the body longer and delivers more benefits for bones‚ blood vessels and other soft tissues.
The Importance of Vitamin K:
Vitamin K‚ a fat-soluble vitamin‚ is primarily known for its role in regulating blood coagulation. Vitamin K is required for the activity of specialized proteins that control blood clotting (Coagulation factors II‚ VII‚ IX) in a series of metabolic steps known as the coagulation cascade. The daily intake of vitamin K recommended by the National Academy of Sciences is based on the amount needed for biosynthesis of these clotting factors in the liver.
Vitamin K-dependent proteins are also found in bone and soft tissues‚ including osteocalcin‚ the protein that deposits calcium in bone. Activation of vitamin K-dependent proteins occurs through carboxylation‚ a metabolic process that adds a molecule composed of carbon‚ hydrogen and oxygen to glutamate‚ an amino acid within the protein structure. (Vitamin-K dependent proteins are also referred to as “Gla proteins.”) Osteocalcin cannot perform its function of incorporating calcium into bone unless it is activated first. A rise in the amount of inactive (under–carboxylated) osteocalcin circulating in the blood is now regarded as a measure of vitamin K deficiency. Vitamin K supplementation has been shown to decrease blood levels of inactive osteocalcin.
Studies report finding elevated levels of inactive osteocalcin in post-menopausal and elderly women. Other studies bring to light a connection between inactive osteocalcin and the deterioration of bone quality and strength that occurs with aging. In view of this‚ it is probably not coincidental that elderly women with superior vitamin K status have had better bone outcomes‚ when compared to other women in the same age groups.
The importance of vitamin K for bone health was underscored by the findings of a 10-year dietary analysis of 72‚327 women in which higher dietary intake of K and superior vitamin K status were associated with a better outcome marker of bone health.
While osteocalcin is essential for keeping calcium in bone‚ Matrix Gla Protein (MGP)‚ another vitamin-K dependent protein‚ helps keep calcium from accumulating in soft tissues where it doesn’t belong‚ thereby supporting vascular health.
As with osteocalcin‚ MGP must be carboxylated to be activated. A recent study found a strong connection between blood levels of active MGP and arterial health. Previous research discovered a link between vascular health and proper vitamin K nutrition.
Forms of Vitamin K:
Vitamin K exists in two major forms: phylloquinone and the menaquinones. Phylloquinone‚ designated as vitamin K1‚ is the major dietary form in food and supplements. Menaquinones‚ designated as vitamin K2‚ are synthesized in the large intestine by gut bacteria‚ although how much this contributes to the body’s vitamin K supply is somewhat uncertain. Menaquinones are named MK-7‚ MK-8 and MK9‚ according to the length of structurally related molecular side chains attached to the parent molecule. Fermented foods contain substantial amounts of K2‚ produced by bacteria that cause the fermentation. MK-7 is the primary menaquinone found in fermented foods such as natto. Two menaquinones are available in dietary supplements; MK-4‚ a synthetic vitamin K2‚ and MK-7‚ which is natural. MK-7‚ thanks to its longer side chain‚ is more stable in the bloodstream than vitamin K1. Recent research reveals that MK-7 contributes to optimum vitamin K storage in the body‚ and functions more effectively as a co-factor for the activation of osteocalcin that is so critical for bone strength‚ as discussed above. This characteristic of vitamin K2 is a major advantage‚ in view of evidence that very high intakes of vitamin K1‚ on the order of 1000 mcg daily (more than ten times the RDI)‚ are needed to maintain optimum levels of activated osteocalcin. For older women in particular‚ consuming vitamin K1 at the current RDI may not be sufficient to achieve vitamin K’s bone health benefits.
Benefits of Natural Vitamin K2 MenaQ7:
- Supports Bone Health and Soft Tissue Elasticity.
- Delivers Optimum Levels of Vitamin K to Bone and Soft Tissue.
- Supports Calcium Metabolism for Maintenance of Healthy Bone.
Serving Size: 1 Capsule
Servings Per Container: 180
Amount Per Serving / % DV
Vitamin K (as Vitamin K2 from 45 mcg of MenaQ7®) 45mcg / 56%
Other Ingredients: Modified cellulose (vegetarian capsule)‚ magnesium stearate (vegetable source)‚ maltodextrin‚ fatty acids.
Non-GMO and Gluten Free.
Contains nothing other than listed ingredients.
Take 1 capsule daily‚ with or without food.
Contains Soy. This product contains Vitamin K. Consult your physician if using blood-thinning medications such as Coumadin/Warfarin.
Allergy / Dietary Needs
- Gluten Free
- Vegetarian Product
- Vegan Product
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Overall Rating for Natural Vitamin K2 MenaQ7 45 mcg 180 Veggie Caps
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from Coral Gables, FL
Great for bones
This supplement is a gem. Great for maintenance of strong healthy bones.
√ I would recommend this item to a friend.
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