Best Acetyl L-Carnitine 588 mg 60 Capsules

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  • Brand: Doctors Best
  • Item Number: DRB1052
  • Serving Size: 1 Capsule(s)
  • Servings per Container: 60
  • Amount per Container: 60 Capsules
  • Price per Serving: $0.20
  • Price per Unit*: $0.20
  • * Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Regular Price: $21.99 $11.70
 
  • Availability: 7 In Stock
  • This item will ship tomorrow when ordered after 5pm EST

 
  • MFG # DRB-00105
  • UPC # 753950001053
  • Science-Based Nutrition
    Dietary supplement
    Beneficial antioxidant protection
    Enhances alertness and mental focus
    Supports energy metabolism in the brain
    Keeps nerves healthy and in repair
    Decreases free radical production in the brain

    Acetyl-L-Carnitine (ALC) is a naturally occurring form of L-Carnitine‚ a vitamin-like nutrient synthesized in the body from the amino acids lysine and methionine. ALC plays a key role in the production of acetylcholine‚ an important neurotransmitter for brain and nerve cell function.

    The Acetyl-L-Carnitine in this product is derived from a base of pharmaceutical grade L-Carnitine manufactured by patented‚ FDA-approved process that fully complies with the USP 25‚ FCC 4 and EU monographs. It is GMO-free‚ pesticide-free and BSE safe.

    Benefits:

    Supports Cognitive Function

    ALC has been studied for its effect on cognitive performance and emotional health in the elderly. In a single-blind‚ placebo-controlled trial‚ 481 elderly subjects taking 1500 mg of ALC per day were found to have improved scores on a memory test assessing cognitive abilities after 90 days of ALC supplementation. In addition to being known for its effects on recognition and memory‚ placebo-controlled ALC research has also shown better scores in scales measuring the mood of elderly people.

    Supports Biosynthesis of Acetylcholine‚ a Key Neurotransmitter for Brain and Nerve Function

    Brain function requires coordinated communication between brain cells. Neurons (brain & nerve cells) communicate across tiny cell-to-cell gaps called synapses. The passage of an electrical impulse from one neuron to the next requires a neurotransmitter to act as a messenger to pass signals to adjacent neurons. When an electrical signal arrives at the synaptic junction‚ the neuron releases a neurotransmitter into the synapse. The neuron on the other side of the synapse contains receptors for the neurotransmitter (that will bind it)‚ triggering a series of chemical events to send a new electrical signal down the membrane of the receiving neuron. Neurotransmitters work together like an orchestra to transmit information throughout the brain and nervous system.

    Acetylcholine is the most abundant neurotransmitter in the body‚ regulating activities of vital organs and blood vessels‚ and communication between nerves and muscles. In the brain‚ acetylcholine helps to facilitate memory and learning‚ as well as influencing emotions. ALC is structurally similar to acetylcholine— enough so that brain neurons stimulated by acetylcholine are receptive to stimulation by ALC. In an experimental animal model‚ it was shown that ALC can furnish acetyl groups to be utilized during the natural biosynthesis of acetylcholine. ALC’s structural similarity to acetylcholine has led researchers to investigate its effects on mental function and emotional health.

    Helps Supply the Brain With Energy Through Mitochondrial Efficiency*

    The acetyl groups donated by ALC can be used to naturally synthesize acetyl-CoA‚ the key substrate for energy metabolism in the mitochondrion. Acetyl-CoA enters the Krebs cycle‚ the mitochondrial pathway that generates cellular energy in the form of ATP. Age-related decreases in mitochondrial oxidative capacity are a well-known cause of aging‚ as the organelles and organs in the body begin to operate less efficiently without ideal ATP production. The effects of decreased mitochondrial oxidative capacity are especially prevalent in organs that require high-energy inputs‚ such as the brain and heart. Recent clinical studies have shown that ALC helps to promote and maintain healthy mitochondrial function.

    Helps Uphold the Integrity of Intracellular Membranes

    Phospholipids are structural components of brain cell membranes that regulate neuronal function. ALC has been shown to promote healthy membrane phospholipid metabolism in research subjects. Additionally‚ the acetyl groups in ALC are naturally utilized by the body to modify the activity of proteins in neuronal membranes. Through these means‚ ALC promotes normal membrane function‚ stability‚ and structural integrity.

    Supports Nerve Growth Factor Production

    The body produces specialized proteins called growth factors that are essential to the growth and repair of tissue. Nerve Growth Factor (NGF) prolongs the survival of neurons in both the central and peripheral nervous systems. As we age‚ our central nervous system experiences a decrease in the binding of NGF to neuron membranes. ALC has shown the ability to promote the maintenance of normal interactions between NGF and neuron membranes. Given to aged rats‚ ALC demonstrated effectiveness in promoting normal levels of NGF‚ and it helped maintain utilization of the growth factor in the rats throughout the duration of the study. Maintaining ideal levels of NGF is essential for the health of cholinergic neurons (nerve cells stimulated by acetylcholine)‚ as cholinergic neurons lose some functional capacity due to a lack of NGF. In aged rats‚ ALC is known to promote the health of cholinergic neurons. In sum‚ such results suggest that ALC positively influences the maintenance of healthy and normal NGF activity.

    Supports Healthy Brain Neuron Function

    Several animal studies have revealed that ALC contains many biochemical characteristics that help neurons face the aging process optimally. ALC has been shown to raise levels of glutathione‚ a key antioxidant‚ in isolated mouse brain tissue. ALC also reduces blood levels of MDA (malondialdehyde)‚ a free radical byproduct. Furthermore‚ ALC is a chelator of iron: it acts as a molecule that can naturally sequester iron in the body to prevent iron-mediated oxidative damage to cells. As a whole‚ data from in vitro and animal studies suggest that ALC is effective towards the maintenance of healthy brain neurons and normal neuronal energetic processes. This hypothesis is supported by human studies that demonstrate the potential of ALC to promote healthy brain function in elderly persons.



    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Official Website: http://www.drbvitamins.com

Serving size: 1 Capsule
Servings Per Container: 60

Amount Per Serving %DV

Acetyl-L-Carnitine 500 mg †
(from 588mg acetyl-l-carnitine HCl supplied by Sigma tau)
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† Daily Value not established.

Other Ingredients: stearic acid‚ cellulose‚ magnesium silicate‚ silicon dioxide‚ gelatin capsule.

Contains nothing other than listed ingredients.

Does Not Contain: milk‚ egg‚ wheat‚ gluten‚ corn‚ soy‚ sugar‚ sweeteners‚ starch‚ salt‚ or preservatives.

As a dietary supplement‚ take 1 to 4 capsules daily with or without food.

ALC is considered safe and well tolerated when consumed orally. Taken as directed by the label‚ the maximum daily dosage of this product is 4 capsules per day‚ well within the limits reported by human safety studies of ALC using the Observed Safety Level (OSL) method.

  • GMP Certification
  • Heavy Metals Free
  • Made In The Usa
  • Milk Free
  • Egg Free
  • Wheat Free
  • Gluten Free
  • Corn Free
  • Soy Free
  • Sugar Free
  • Starch Free
  • Salt Free
  • Preservative Free
  • Pesticide Free

Ratings & Reviews

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Overall Rating for Best Acetyl L-Carnitine 588 mg 60 Capsules

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5 4 Based on 4 reviews

Displaying reviews 1-4 of 4

  • By
    from Atlanta, GA

      5
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    1/31/2014

    More energy and mental clarity

    I love Doctor Best products and this Acetyl-L-Carnitine is one of the best. Acetyl-L-Carnitine is an advanced form of L-Carnitine and works to improve the immune system energy production and gives a boost to mental clarity focus and concentration. It is also good for muscles including the heart. I know my memory is better and I have more energy I take this every day and will continue to do so.

    Pros

      Great company!

    Cons

      Do not take too late in the day or may impact your sleep.

    I would recommend this item to a friend.

     
  • By
    from Cocoa, FL

      5
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    9/06/2013

    Awesome price awesome product!

    With Best Acetyl L-Carnitine I am trying it for the first time and so far I really like it. Aside from being swayed to buy this by the fact that this is a Doctors Best brand product and at a great price which is usual for a lot of their products I like the fact that Im not getting just any old Acetyl L-Carnitine; Im getting a high quality one! I get stuck with a lot of evening shifts at work and I have to talk to people constantly so I find that most nights when I get home I feel so mentally drained. My experience with Best Acetyl L-Carnitine so far is that those feelings have lessened and I can actually go home following a long shift and be able to get more accomplished around the house before calling it a night. I just take one in the late afternoon or evening. I was faced with a choice of either taking this or taking regular L-Carnitine and I am happy to have chose this. Ill let the weights deal with fat burning and let Doctors Best help to keep my head right!

    Pros

      I have had products of this brand before and have had a great experience! I think that I feel a difference when I take this product so thats awesome! The pill isnt too big and can be taken with or without food if I dont have time to eat. As

    Cons

      NO DISLIKES!

    I would recommend this item to a friend.

     
  • By
    from Coral Gables, FL

      5
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    7/24/2013

    Great focus

    I focus better when I use Best Acetyl L-Carnitine. Low price affordable for anyone.

    I would recommend this item to a friend.

     
  • By
    from Miami Beach, FL

      5
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    11/20/2012

    mental focus best

    I take Best Acetyl L-Carnitine 588 mg in combination with ginkgo and I do feel more alert better concentration and ever more energy great service also thank you

    Pros

      price effective recognized brand

    Cons

    I would recommend this item to a friend.

     

Displaying reviews 1-4 of 4

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