Pure Encapsulations   SAMe (S-Adenosylmethionine) - 60 Capsules

Shop all Pure Encapsulations products

"I’ve been taking Pure Encapsulations SAMe for about six months. My body does not..."  Read all reviews

Item Number: PE1991
Serving Size: 1 Capsule Servings per Container: 60
Price per Serving:  $1.27 Price per Unit*: $1.27 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
47 In Stock.

This item will ship on Monday before 5PM EST.


Save $3.80

Save on every shipment + earn Reward points.

- +

Boost your cardiovascular health with this highly tolerated niacin form. Experience enhanced stability and support for methylation‚ positive mood‚ glutathione production‚ and joint comfort with this SAMe supplement.‡

Discover the incredible benefits of SAMe: a powerful metabolite found in all living cells. With over 100 different reactions‚ SAMe plays a crucial role in the synthesis and metabolism of hormones‚ neurotransmitters‚ nucleic acids‚ phospholipids‚ and proteins. By regulating genetic expression and cellular function‚ SAMe acts as a vital signal throughout the body. Don't miss out on the opportunity to enhance your cellular health‚ hormone production‚ neurotransmitter function‚ and energy metabolism. SAMe also supports glutathione production‚ promotes healthy cellular function‚ and maintains cytokine balance for optimal cell growth. Experience the proven benefits of SAMe‚ as clinical trials have shown its ability to improve cognitive function‚ mood‚ joint comfort‚ and flexibility. By supporting methylation reactions‚ SAMe even promotes phosphatidylcholine production and enhances cellular membrane integrity and fluidity. Don't wait any longer to enjoy the benefits of SAMe - unlock a healthier‚ more vibrant version of yourself today.‡

Benefits & Features:
• Supports methylation and glutathione production‡
• Promotes cognitive health and positive mood‡
• Enhances joint comfort‚ flexibility and integrity‡
• Provides support for neurotransmitter synthesis‚ cell membrane fluidity and healthy cell growth‡
• Provides enhanced stability SAMe
• Made with high-quality vegan ingredients backed by verifiable science

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # SAM6
  • UPC # 766298015040
Official Website: https://www.pureencapsulations.com

Serving Size: 1 Capsule
Servings Per Container: 60

Amount Per Serving / % DV

SAMe (S-adenosylmethionine) 200mg / *
(From S-Adenosyl-L-Methionine disulphate tosylate)

*Daily Value not established.

Other Ingredients: Vegetarian capsule (cellulose‚ water)‚ hypoallergenic plant fiber (cellulose)‚ calcium oxide‚ ascorbyl palmitate‚ calcium chloride.

Sourced and manufactured to avoid: Artificial additives‚ allergens‚ GMOs‚ environmental contaminants‚ added excipients.


As a dietary supplement‚ take 1 capsule‚ 1-2 times daily‚ between meals‚ or as directed by a health professional.

Store sealed in a cool‚ dry area.

Tamper Resistant; Use only if safety seal is intact.

If you are pregnant or lactating‚ have any health condition or are taking any medication‚ particularly if you have bipolar disorder or are taking antidepressant medication‚ consult your health professional before use.

Keep out of the reach of children.

  • Egg Free
  • Gluten Free
  • Non-GMO
  • GMP
  • Made in the USA
  • Peanut Free
  • Wheat Free
  • Hypoallergenic

Ratings and Reviews

Write a Review

Customer Questions and Answers

1-2 of 2

  • Question:
    Instructions say to take this between meals. Please clarify. Does this mean on an empty stomach? If so, how long before and after eating anything is considered an empty stomach?. Thanks.
    B J Waring on 7/17/2015 Answer:
    • Thank you for contacting us B J, yes this prodcut should be taken 20-30 minutes after a meal.
      Christopher on 7/17/2015
  • Question:
    I contacted Pure Encapsulations regarding cooler shipment. They said this item does not require refrigeration now. Can you please confirm this is the case? Thanks!
    Jamie Engel on 6/18/2015 Answer:
    • Thank you for reaching out to us, Jamie. Pure Encapsulations has advised us that this product is mandatory to ship with the ice-cooler. In order to maintain the integrity of the product, we must ship with the cooler until they advise us otherwise. Please contact us at 800-383-6008 with any concerns. 
      PureFormulas on 6/18/2015

Ask a Question

Please log in to submit a question Log In