Description
- MFG # DRB-00252
- UPC # 753950002524
Doctor’s Best SAM-e is proven to enhance mood and promote cognitive health. It is essential for the healthy metabolism of the major brain transmitters’ dopamine‚ serotonin and norepinephrine. In addition‚ SAM-e promotes joint comfort and mobility and supports liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human trials published over 40 years. Doctor’s Best SAM-e uses pharmaceutical grade materials. SAM-e is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. SAM-e optimized for potency‚ stability‚ and to survive the stomach acid and reach the intestine (where it is absorbed). Effectiveness of SAM-e has been backed by at least 18 controlled human trials published over almost four decades.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Ingredients
Serving Size: 1 Tablet
Servings Per Container: 60
Amount Per Serving / % DV
S-Adenosyl Methionine (From 800mg of SAM-e tosylate disulfate) 400mg / †
†Daily Value not established.
Other Ingredients: Microcrystalline cellulose‚ magnesium hydroxide‚ stearic acid‚ calcium chloride anhydrous‚ magnesium stearate‚ colloidal silica anhydrous‚ calcium oxide‚ magnesium silicate‚ natural food glaze‚ arginine base‚ glycerol‚ sodium alginate.
Gluten-Free / Soy-Free / Vegan / Vegetarian.
Dosage
Take 1 tablet daily between meals‚ or as recommended by a nutritionally informed physician.
Precautions
Do not chew or crush tablet.
Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
Individuals diagnosed with bipolar disease or manic depression should avid supplementing with SAMe.
Do not use if pregnant or nursing.
Store in a cool‚ dry place.
Notice: May cause gastrointestinal discomfort in a small percentage of people.
Allergy / Dietary Needs
- Gluten Free
- Soy Free
- Vegan
- Vegetarian
Ratings & Reviews
Review This ItemOverall Rating for Double-Strength SAM-e 400 mg - 60 Enteric Coated Tablets
Displaying reviews 1-10 of 14
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By grandma
from oregon7/29/2015
Very effective!
Adult child has anxiety and panic attacks. SAM-e by Doctor's Best has been helpful.
Pros
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Effective.
Cons
√ I would recommend this item to a friend.
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By Ruth Sanchez
from connecticut3/18/2015
I love it!
I enjoy taking SAM-e by Doctor's Best and I love the way it helps me!
Pros
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The way it makes me feel!
Cons
√ I would recommend this item to a friend.
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By SSJ
from United States of America1/24/2015
Great Mood Support
I take 800 mg. in the morning for mood support along with Gaia Herbs St. John's Wort. I did not notice a difference when taking only 1 pill (i.e. 400 mg) a day but I got mood improvement from taking 2 pills.
Pros
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Like how the pills are packaged.
Cons
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Expensive and the list of additives are unrecognizable ingredients are quite long! Wish there was a SAM-e product out there without all the additives.
√ I would recommend this item to a friend.
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By Teresa Cornwell
from Virginia12/11/2014
GREAT VALUE!!
My husband takes the Sam-E by Doctor's Best for liver support, ( prescribed by his Dr) which has been excellent. He also reaps the benefit of it being a mood elevator. It also helps with joint discomfort and better joint function. He has had a very good experience with it. Just remeber, if you tend to be bi-polar, this is NOT for you!! see the warnings about SAM E .
Pros
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Excellent value and wonderful product.
Cons
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None.
√ I would recommend this item to a friend.
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By Sharon Troester
from Birdsboro,PA11/21/2014
SAM-e
Taking Doctor's Best SAM-e has helped keep my energy levels up.
Pros
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Tablets are individually packaged. This makes it easy for taking them with you and keeping them fresh.
Cons
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Nothing.
√ I would recommend this item to a friend.
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By D
from chig4/22/2014
helping my dog with high liver enzymes
Helps to bring my dogs liver enzymes into the lower high range
Pros
Cons
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price for sam-e products make it cost prohibitive for me to take also although this brand is less expensive
√ I would recommend this item to a friend.
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By Donia
from Kapaa, HI1/31/2014
Didnt work for me
I tried these and unfortunately they didnt work and are very expensive. But obviously with these types of things everyones body chemistry is different.
Pros
Cons
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Very Expensive
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By Lynn
from NW Arkansas1/10/2014
Take the GI precaution seriously
Normailly I dont have any GI issues with supplements and I take quite a few. I have osteoarthritis in my hip and have read that sam-e was fairly effective for osteoarthritis. The directions take away from food has to be one of the worst written instructions on a supplement. What does that mean? An hour after eating an hour before eating 2 hours 3 hours? I took it several hours after lunch for the first time. Major stomach ache. I re-read the box and noticed: May cause GI discomfort in a small percentage of people. I think they need to put that in BOLD. After reading reviews of sam-e and the GI problems that many people had I read that the best time to take it was first thing in the morning with a full glass of water. They should think about including that in the instructions. That worked for the stomach ache. Not sure what to do about the GI issues like loose stools. Ive taken it for about 5 days and Im debating whether to continue as I have not seen any benefit worth the discomfort and cost. It also seems to have the effect (like too much coffee) of feeling jittery. I was worried that it might keep me from sleeping but that didnt prove to be an issue.
Pros
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Not sure
Cons
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GI issues jitteriness
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By Giovanni
from Coral Gables, FL7/23/2013
Works a lot better
SAM-e works a lot better than regular SAM E from Doctors best. Double strength is much more effective.
√ I would recommend this item to a friend.
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By Lorie
from Apex, NC4/13/2013
SAMe
SAM-e has great quality and Ive tried others but like this one the best. SAM-e helps me think clearer and keep my thoughts. Others have reported that they get anxious or experience insomnia but I have not experienced any of that. I am taking SAM-e under the consult of my doctor.
√ I would recommend this item to a friend.
Displaying reviews 1-10 of 14
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Questions About This Item
Ask a QuestionPlease ask any questions you may have about this specific product in the field below.
Your question(s) and our corresponding answer(s) will not be confidential and will be posted publically on this specific product page.
Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.
If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008
If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.
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