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Jarrow Formulas   SAM-e 400 mg - 60 Tablets

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4 Reviews

"Eased my depression"  Read all reviews

Item Number: JF1366
Serving Size: 1 Tablet Servings per Container: 60
Price per Serving:  $0.94 Price per Unit*: $0.94 per Tablet
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
42 In Stock. This item will ship today if ordered within 10 hr 48 min
Regular Price:  $76.50 $56.53
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Highest Concentration of Active S‚S form!

Jarrow Formulas® SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Found in all living cells‚ SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S‚S) SAM-e and (R‚S) SAM-e. The biologically active form is the (S‚S) structure‚ while the (R‚S) structure is biologically inactive. Jarrow Formulas® SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S‚S) SAM-e‚ the highest active level available.

- Joint strength.
- Liver detoxification.
- Mood and brain function.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # SAM460
  • UPC # 790011200420
Official Website:

Serving Size: 1 Tablet
Servings Per Container: 60

Amount Per Serving / % DV

S-Adenosyl Methionine 400mg / *
(From 800mg of SAM-e tosylate disulfate)

*Daily Value not established.

Other Ingredients: Cellulose‚ glyceryl behenate‚ magnesium stearate (vegetable source)‚ silicon dioxide‚ mannitol‚ sodium starch glycolate‚ and an enteric coating (methacrylate copolymers‚ magnesium silicate‚ titanium dioxide‚ triethyl citrate‚ silicon dioxide and riboflavin).

No wheat‚ gluten‚ soybeans‚ dairy‚ egg‚ fish/shellfish‚ peanuts/tree nuts.

Vegan / Vegetarian.

Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.

Individuals using prescribed medications such as antidepressants‚ including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product.

Individuals with Parkinson's disease‚ bi-polar disorder or manic depression should not use SAM-e.

Do not use if pregnant or nursing.

Do not exceed recommended intake.

May cause gastrointestinal upset in some persons. If you experience discomfort‚ discontinue use.

Store in a cool‚ dry place.

Keep out of the reach of children.

  • Dairy Free
  • Egg Free
  • Fish Free
  • Gluten Free
  • Nut Free
  • Peanut Free
  • Soy Free
  • Vegan
  • Vegetarian
  • Wheat Free
  • Crustacean Shellfish Free

Ratings and Reviews

Write a Review
  • 5.0
5 4
  • 4 Reviews
    • Verified Buyer

      Tremendous help!

      from Medina OH on 1/17/2022
      Eased my depression


      Not a prescription drug


      No cons at all
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Keeps me from feeling flat

      from WAUKESHA WI on 9/23/2019
      I take this after having it prescribed by my naturalpath after taking a brain chemistry test. I had not been feeling sad, but really not happy or sad about much for a couple of years and decided to take action and talk to my doctor. I won't say that I am super happy all the time, but now I don't feel flat and affected. I am able to feel joy and sad at the levels that I remember.
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      so helpful for depression

      from ROSEVILLE CA on 9/05/2019
      I've been taking an anti-depressant for a couple of decades and found myself needing a boost. I learned that my brain actually needs help CREATING serotonin, which isn't done through the use of SSRI's. SAM-e has been extremely helpful. And this particular kind is reliable. I like to get the larger package so that each dose is less expensive and I have to buy it less frequently.


      It works to boost mood level when depression is a factor.


      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Great so far

      from New York NY on 5/19/2019
      Produce has worked well, the higher concentration is also more convenient


      Felt great


      Need to ramp up dose slowly
      review-checkI would recommend this item to a friend.

Customer Questions and Answers

1-1 of 1

  • Question:
    Can these be cut in half for a morning/evening dose?
    Michael Reineck on 2/11/2016 Answer:
    • Hi there Michael. Great question. Yes you can cut in half for a morning/evening dose.
      PureFormulas on 2/11/2016

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