- MFG # 01430
- UPC # 737870143062
Findings from published scientific literature indicate that resveratrol may be the most effective plant extract for maintaining optimal health and promoting longevity. Resveratrol is a phytoalexin‚ a natural plant antibiotic which is produced by Vitis vinifera as a response to attack by molds. Because of the widespread use of pesticides in modern wine making‚ including the practice of copper sulphation‚ the level of resveratrol in modern wines has plummeted. Red wine contains resveratrol‚ but the quantity varies depending on where the grapes are grown‚ the time of harvest and other factors. In fact‚ usually only one to three mg of resveratrol per liter of red wine is currently found‚ even in the most robust red wines. After years of relentless research‚ a standardized resveratrol extract is now available as a dietary supplement.
Research funded by the Life Extension Foundation showed that a combination of low-dose (20 mg) resveratrol plus grapeseed extract mimicked many of the favorable gene expression changes seen in calorie-restricted animals. Other studies‚ however‚ indicate that higher doses may be needed to obtain all of resveratrol’s positive benefits including promoting healthy insulin sensitivity‚ enhanced mitochondrial function‚ reduced expression of inflammatory factors‚ and protection against the toxic effects of a high-fat diet.
Life Extension has evaluated published studies on resveratrol to establish the doses humans might need to take to duplicate the remarkable laboratory findings. The results of Life Extension’s analysis yield a wide range of potentially effective doses: from 20 to 250 mg a day and higher. The resveratrol potency you choose may be based on your current state of health and/or your desire to reach the upper limits of a healthy human life span.
Pterostilbene‚ a stilbene compound from the same family as resveratrol‚ has been shown to work synergistically with resveratrol‚ to unlock one’s longevity genes … thus conferring even greater anti-aging benefits.
Life Extension has identified certain compounds that mimic calorie restriction’s ability to trigger youthful gene expression‚ the process by which genes transmit signals that slow certain aspects of aging. These compounds include trans-resveratrol (which researchers contend is the most active constituent)‚ grapeseed extract‚ quercetin‚ plus certain compounds found in berries‚ including trans-pterostilbene and now fisetin.
Fisetin‚ for example‚ found in strawberries‚ has the power to “switch on” cell signaling molecules that support youthful gene expression‚ DNA protection‚ and healthy cellular function. Fisetin also supports aging neurons in the presence of oxidative stress. And‚ most importantly‚ it works in synergy with resveratrol. Researchers have uncovered compelling evidence of fisetin’s ability to stabilize resveratrol by shielding it from metabolic breakdown‚ thus extending its beneficial effects! So naturally we added it‚ along with these other four calorie restriction mimics‚ to this most advanced resveratrol formulation.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size 1 Vegetarian Capsule
Servings Per Container 60
Amount Per Serving
Trans-resveratrol [from Polygonum cuspidatum extract (root) and whole red grape (Vitis vinifera) extract] 250 mg
Red Grape (Full Spectrum French Red Wine Polyphenol Profile)‚ Wild Blueberry (Vaccinium angustifolium)‚ and Polygonum cuspidatum extract blend [supplying polyphenols‚ anthocyanins‚ OPCs‚ free resveratrol‚ resveratrol conjugates (epsilon-viniferin‚ trans and cis-polydatin)‚ and resveratrol analogs (pterostilbene)] 85 mg
Quercetin (as quercetin dihydrate) 60 mg
Trans-Pterostilbene (as pure Pterospan™ and SMART™† pterostilbene) 0.5 mg
Fisetin [from (Rhus succedanea L.) extract (stem)] 10 mg
Other ingredients: vegetable cellulose (capsule)‚ microcrystalline cellulose‚ silica‚ vegetable stearate‚ maltodextrin.
Take one capsule daily with or without food‚ or as recommended by a healthcare practitioner.
If you are taking anti-coagulant or anti-platelet medications‚ or have a bleeding disorder‚ consult your healthcare provider before taking this product.
Store tightly closed in a cool‚ dry place.
Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements‚ please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Allergy / Dietary Needs
- Vegetarian Product
Ratings & ReviewsReview This Item
Overall Rating for Optimized Resveratrol with Synergistic Grape-Berry Actives 250 mg 60 Vegetarian Capsules
By Nancy Borntreger
from Lancaster, PA
Life Extension has excellent products. Optimized Resveratrol with Synergistic Grape-Berry Actives helps fight cancer, alzheimer's, diabetes and heart disease.
√ I would recommend this item to a friend.
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