Optimized Folate (L-Methylfolate) 1000 mcg - 100 Vegetarian Capsules

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  • Average Rating: 5.0
  • Item Number: LE1234
  • Serving Size: 1 Vegetarian Capsule
  • Servings per Container: 100
  • Quantity per Container: 100 Vegetarian Capsules
  • Price per Serving: $0.21
  • Price per Unit*: $0.21 per Vegetarian Capsule
  • * Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Regular Price: $28.00 $21.00
 
  • Availability: 29 In Stock
  • This item will ship today if ordered within 4 hr 36 min
 
  • MFG # 01439
  • UPC # 737870193913
  • Metabolically Active Form of Folic Acid.

    Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine‚ folate benefits cardiovascular health and nervous system function.

    Those who take ordinary folic acid supplements‚ however‚ may not be experiencing its full spectrum of effects. This is because folic acid is itself not biologically active‚ but its biological importance is due to its active form called 5-methyltetrahydrofolate (5-MTHF) after its conversion to dihydrofolic acid in the liver. Research shows that in a large proportion of the population‚ genetic dihydrofolate reductase enzyme deficiencies limited the conversion of folate to 5-MTHF‚ leaving many vulnerable to low blood 5-MTHF levels (and higher than desired homocysteine).

    A more useful approach is to take the bioactive folate 5-MTHF directly‚ which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate levels compared with folic acid supplementation. 5-MTHF is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since 5-MTHF requires no conversion to be biologically active.

    People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid‚ 5-MTHF is able to cross the blood-brain barrier‚ which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

    Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12)‚ vitamin B6‚ and riboflavin.

    Optimized Folate now provides Quatrefolic® 5-methyltetrahydrofolate complexed with glucosamine for longer stability‚ higher water solubility and improved bioavailability compared to other forms of 5-MTHF.

    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Official Website: http://www.lef.org

Serving Size 1 Vegetarian Capsule
Servings Per Container 100

Amount Per Serving % Daily Value

Folate [as (6S)-5-Methyltetrahydrofolic acid‚ glucosamine salt]^ 1000 mcg 250%

Other ingredients: microcrystalline cellulose‚ vegetable cellulose (capsule)‚ silica‚ vegetable stearate.

Take one capsule daily with food‚ or as recommended by a healthcare practitioner.

Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements‚ please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Store tightly closed in a cool‚ dry place.

  • Vegetarian Product

Ratings & Reviews

Review This Item

Overall Rating for Optimized Folate (L-Methylfolate) 1000 mcg - 100 Vegetarian Capsules

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  • Average Rating: 5.0
5 13

Displaying reviews 1-10 of 13

  • By
    from Georgia

      5
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    4/17/2015

    Best form of folate!

    I like that Optimized Folate by Life Extension is the best form of folate and great for someone with MTHFR gene. The capsules are easy to swallow and the strength is high, which I like.


    I would recommend this item to a friend.

     
  • By
    from Southeast

      5
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    1/01/2015

    Great product!

    I take Optimized Folate by Life Extension as I have a double mutation of the MTHR. No side effects at all.


    I would recommend this item to a friend.

     
  • By
    from Arizona

      5
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    12/09/2014

    Great

    I used to use plain folic acid but my doctor recommended switching to Optimized Folate (L-Methylfolate) by Life Extension as it is more biologically active.


    Pros


    Cons

      Nothing.

    I would recommend this item to a friend.

     
  • By
    from NYC

      5
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    12/09/2014

    L-Methylfolate

     Optimized Folate by Life Extension is the best form of folate. Life Extension makes great products.


    I would recommend this item to a friend.

     
  • By
    from walla walla

      5
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    11/15/2014

    great price, great product

    In conjunction with pure lean encapsulations that include additional 800mcg and 500mcg of b12 it males me feel really good and clear headed.


    Pros

      Easy to take

    Cons

      None

    I would recommend this item to a friend.

     
  • By
    from St. Louis

      5
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    9/22/2014

    Helps Depression meds

    Optimized Folate by Life Extension is very similar to a prescription med that my psychiatrist prescribed to assist my depression meds work better. This is the only over the counter solution I've found now that my insurance won't cover the script.


    Pros

      Nice size capsule, not too big.

    Cons

      Have to take a bunch to equal the prescription dosage.

    I would recommend this item to a friend.

     
  • By
    from United States

      5
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    2/12/2014

    Excellent product! High quality!

    Excellent product! High quality!


    I would recommend this item to a friend.

     
  • By
    from East Hampton, CT

      5
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    12/08/2013

    Health Benefit

    Was unable to process folic acid and after researching a natural alternative to folast I purchased this product. I have been very pleased with the results.l


    I would recommend this item to a friend.

     
  • By
    from savannah, ga

      5
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    12/03/2013

    Helps with depression.

    I notice when I run out of this product that I start getting depressed again. I take about 7 of them a day. One of the latest antidepressants on the market is a concentrated dose of this same form of B vitamin so I figured I would take a high dose and it works.


    I would recommend this item to a friend.

     
  • By
    from Missouri

      5
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    7/06/2013

    Good product

    Optimized Folate is just what my sons doctor wanted him to take.


    Pros

      Good price

    Cons


    I would recommend this item to a friend.

     

Displaying reviews 1-10 of 13

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