Optimized Folate (L-Methylfolate) 1000 mcg - 100 Vegetarian Tablets

by Life Extension
    4.9
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"Excellent product! High quality!"  Read all reviews

Quantity per Container: 100 Tablets
Item Number: LE1234
Serving Size: 1 Tablet Servings per Container: 100
Price per Serving:  $0.11 Price per Unit*: $0.11 per Tablet
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
11 In Stock. This item will ship today if ordered within 6 hr 38 min
Regular Price:  $15.00 $11.25
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    Metabolically Active Form of Folic Acid.

    Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine‚ folate benefits cardiovascular health and nervous system function.

    Those who take ordinary folic acid supplements‚ however‚ may not be experiencing its full spectrum of effects. This is because folic acid is itself not biologically active‚ but its biological importance is due to its active form called 5-methyltetrahydrofolate (5-MTHF) after its conversion to dihydrofolic acid in the liver. Research shows that in a large proportion of the population‚ genetic dihydrofolate reductase enzyme deficiencies limited the conversion of folate to 5-MTHF‚ leaving many vulnerable to low blood 5-MTHF levels (and higher than desired homocysteine).

    A more useful approach is to take the bioactive folate 5-MTHF directly‚ which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate levels compared with folic acid supplementation. 5-MTHF is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since 5-MTHF requires no conversion to be biologically active.

    People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid‚ 5-MTHF is able to cross the blood-brain barrier‚ which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

    Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12)‚ vitamin B6‚ and riboflavin.

    Optimized Folate now provides Quatrefolic® 5-methyltetrahydrofolate complexed with glucosamine for longer stability‚ higher water solubility and improved bioavailability compared to other forms of 5-MTHF.



    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.


  • MFG # 01939
  • UPC # 737870193913
Official Website: http://www.lef.org

Serving Size: 1 Vegetarian Tablet

Amount Per Serving / % DV

Folate [As (6S)-5-Methyltetrahydrofolic Acid‚ glucosamine salt] 1‚000mcg / 250%

Other Ingredients: Microcrystalline cellulose‚ dicalcium phosphate‚ croscarmellose sodium‚ silica‚ vegetable stearate‚ stearic acid.

Non-GMO.

Take one (1) tablet daily with food‚ or as recommended by a healthcare practitioner.

Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements‚ please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. Store tightly closed in a cool‚ dry place.

  • GMO Free
  • Vegetarian

Ratings and Reviews

Write a Review
    4.9
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  • Average Rating: 4.9 out of 5 stars
5 20
20 Reviews
  • Verified Buyer

    Doesn't seem to work for me...

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    from CT on 3/06/2018
    I asked my psychiatrist if there were any supplements I could take that would help with depression without interfering with my medications, and she recommended Optimized Folate by Life Extension. I have been taking this every day along with my usual medications, and I haven't noticed a difference, so I don't think I'll be repurchasing at this time. If I notice a change for the worse after I stop taking it, maybe I will try it again.

    Pros

    Not too sure...

    Cons

    Possibly ineffective.
  • Verified Buyer

    Added to daughter’s regimen

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    from HAZLEHURST GA on 1/31/2018
    This Optimized Folate (L-Methylfolate) 1000 mcg by Life Extension comes in an easy to swallow size. It is a quality product.

    Pros

    The price was great. I believe in the quality of this brand.

    Cons

    Nothing
    I would recommend this item to a friend.
  • Verified Buyer

    Great product!

      5
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    from COLUMBUS OH on 12/23/2017
    My physician recommended Optimized Folate (L-Methylfolate) 1000 mcg by Life Extension to help with anxiety and a disorder that I have called trichotillomania. It has really helped!

    Pros

    It really helps me.

    Cons

    Wish the price was a little less, but will pay more for good quality.
    I would recommend this item to a friend.
  • Verified Buyer

    Pure product

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    from La Pine OR on 10/20/2017
    Optimized Folate (L-Methylfolate) 1000 mcg by Life Extension has helped my folic levels.
    I would recommend this item to a friend.
  • Verified Buyer

    The best!

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    from Arizona on 3/25/2016
    My doctor suggested I take Optimized Folate by Life Extension and I am so grateful she did. I take it every morning and can really tell the difference. It's amazing!

    Pros

    The small tablet is easy to swallow. This brand works better than others I have tried before.

    Cons

    There is nothing that I dislike about this product and I would highly recommend it.
    I would recommend this item to a friend.
  • Verified Buyer

    Don't Be Confused.

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    from Calabasas, CA on 3/14/2016
    Folate and folic acid are not the same; so, when my physician recommended Optimized Folate by Life Exension, I researched, and shopped hardy! Best price, fast delivery, and just what the doctor ordered.
    I would recommend this item to a friend.
  • Verified Buyer

    Lightens my mood!

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    from davis, ca on 10/05/2015
    At the suggestion of a friend, I tried Optimized Folate L-Methylfolate by Life Extension. They are wonderful. I suffer from Major Depressive Disorder and I am treatment resistant, but the product above makes a discernible difference in severity of depressive symptoms. I understand it may not work for everyone, but it certainly works for me.

    Pros

    Eases symptoms of major depressive disorder.

    Cons

    Nothing. :)
    I would recommend this item to a friend.
  • Best form of folate!

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    from Georgia on 4/17/2015
    I like that Optimized Folate by Life Extension is the best form of folate and great for someone with MTHFR gene. The capsules are easy to swallow and the strength is high, which I like.
    I would recommend this item to a friend.
  • Great product!

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    from Southeast on 1/01/2015
    I take Optimized Folate by Life Extension as I have a double mutation of the MTHR. No side effects at all.
    I would recommend this item to a friend.
  • Great

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    from Arizona on 12/09/2014
    I used to use plain folic acid but my doctor recommended switching to Optimized Folate (L-Methylfolate) by Life Extension as it is more biologically active.

    Pros

    Cons

    Nothing.
    I would recommend this item to a friend.
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If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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