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Pure Encapsulations   MotilPro - 180 Capsules

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  • 3.9
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24 Reviews

"I’ve had so many digestive issues, and I truly feel a difference using this prod..."  Read all reviews

Item Number: PE1889
Serving Size: 3 Capsules Servings per Container: 60
Price per Serving:  $0.90 Price per Unit*: $0.30 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
56 In Stock.

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What exactly is gut signaling? It sounds funny‚ but actually entails the way that your gastrointestinal tract talks to your brain. The GI tract tells the brain that something is present in the stomach‚ and the brain then replies with signals that regulate absorption‚ secretion‚ and motility in the intestines.

Motility is the process by which food and waste products get stuck in the gastrointestinal tract. This happens when the normal contractions--called peristalsis--get out of whack. Instead of rhythmic‚ coordinated contractions‚ the contractions become excessively slow‚ rapid‚ or dissappear altogether.

Obviously‚ this can cause discomfort or even worse. MotilPro by Pure Encapsulations may alleviate some mild digestive motility symptoms if they aren't secondary to another health condition. In some cases‚ motility disorders may be genetic.

This supplement contains pyridoxal-5-phosphate (an activated form of vitamin B6)‚ acetyl-l-carnitine (an amino acid)‚ ginger extract‚ and 5-HTP in order to support the entric nervous system. The entric nervous system consists of over 100 million neurons that line the GI tract and communicate with the brain while using neurotransmitters and neurohormones to support coordinated smooth muscle contraction (which allows substances to move throughout the gastrointestinal tract easily).

MotilPro supports the so-called "gut brain" in order to support nutrient and fluid absorption‚ as well as detoxification. In addition‚ you may experience relief in the abdominal area and the upper GI tract. It works primarily by promoting the effective transmission of serotonin and acetylcholine.

Take three to six capsules daily‚ in divided doses between meals. At the recommended dosage‚ each 180-capsule bottle of Pure Encapsulations' MotilPro should last for one or two months.

Pure Encapsulations seeks to formulate and manufacture high-quality‚ hypoallergenic dietary supplements. Quality control during the formulation and manufacturing process is paramount. All Pure Encapsulations products are made with the most bioavailable ingredients possible.



These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # MOP1
  • UPC # 766298013091
Official Website: https://www.pureencapsulations.com

Serving Size: 3 Capsules
Servings Per Container: 60

Amount Per Serving / % DV

Vitamin B6 (As Pyridoxal 5' Phosphate) (Activated B6) 6.7mg / 335%
Ginger (Zingiber Officinale) Extract (Root) 1‚000mg / *
(Standardized to contain 5% Gingerols)
Acetyl-L-Carnitine (Free-Form) 500mg / *
5-Hydroxytryptophan 50mg / *

*Daily Value not established.

Other Ingredients: Vegetarian capsule (cellulose‚ water)‚ ascorbyl palmitate.

Sourced and manufactured to avoid: Artificial additives‚ allergens‚ GMOs‚ environmental contaminants‚ added excipients.

Hypoallergenic.


As a dietary supplement‚ take 3 capsules‚ 1-2 times daily‚ between meals.


Store sealed in a cool‚ dry area.

Tamper Resistant: Use only if safety seal is intact.

Not to be taken by pregnant or lactating women.

If you have any health condition or are taking any medication‚ consult your health professional before use.

Do not use concurrently with SSRI medications or MAO inhibitors.

Keep out of the reach of children.


  • Egg Free
  • Gluten Free
  • GMO Free
  • GMP (Good Manufacturing Practices) Certification
  • Made in the USA
  • Peanut Free
  • Wheat Free
  • Hypoallergenic

Ratings and Reviews

Write a Review
  • 3.9
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4 24
  • 24 Reviews
    • Verified Buyer

      Great prokinetic

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      from Colorado on 9/28/2021
      This prokinetic supports digestion and helps with regularity.

      Pros

      Supports digestion

      Cons

      review-checkI would recommend this item to a friend.
    • Methan-SIBO (IMO)

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      from Tennessee, U.S. on 8/30/2021
      Tried this as I saw its components are quite popular as prokinetics to help methane-predominant SIBO (or IMO). Here's my experience after 5 days, taking 1 capsule about 3-4hrs after lunch and 1 before bed. Pros: Unlike several commenters, I did not find this irritating my stomach. I have gastritis and GERD, so I was pleasantly surprised when this only produced a warming (not burning or painful) sensation. It felt similar to drinking something very warm on an empty stomach, or like the contrast used in CT scans (only isolated to the stomach). Cons: I saw no improvement in constipation at all. It also produced terrible intestinal cramping, like I hadn't had since taking oregano oil and allicin. $60 down the drain in my case, but it may help others. After this purchase, I found one practitioner who found only 10% of SIBO patients she's treated got relief from this product, but that those 10% swore by it. Thought this was worth mentioning.

      Pros

      Did not irritate my stomach; produced a soothing, warming sensation

      Cons

      Did not relieve my constipation; caused gut cramps; price
    • Best herbal prokinetic

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      from Kansas city on 11/06/2020
      Motilpro ensures that my gut works which is SO important to me. Better than any pharmaceutical prokinetic

      Pros

      Cons

      N/A.
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Improves digestion

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      from Baltimore on 9/18/2020
      I ordered these when dealing with SIBO. Ginger is supposed to help with motility. Although my issues were severe and I still needed medicine, I did feel they helped with digestion and were soothing to my painful bloating. Some may feel like they cause indigestion or acid reflux but you must follow the directions and take no sooner than a couple hours after meals and with plenty of water. Sometimes I feel like they stick in my throat. They do produce a warming sensation in your stomach but i felt like this was a soothing feeling, the same way peppermint pills feel.

      Pros

      Helpful for motility and SIBO.

      Cons

      Price.
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Improves digestion

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      from Maryland on 9/18/2020
      I ordered these when dealing with SIBO. Ginger is supposed to help with motility. Although my issues were severe and I still needed medicine, I did feel they helped with digestion and were soothing to my painful bloating. Some may feel like they cause indigestion or acid reflux but you must follow the directions and take no sooner than a couple hours after meals and with plenty of water. Sometimes I feel like they stick in my throat. They do produce a warming sensation in your stomach but i felt like this was a soothing feeling, the same way peppermint pills feel.

      Pros

      Helpful for motility and SIBO.

      Cons

      Price.
      review-checkI would recommend this item to a friend.
    • It works

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      from Ct on 8/31/2020
      I’ve only been using for a week, but it seems to keep things moving.

      Pros

      Cons

      N/A 
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Didn't work for me at all!

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      from Snohomish WA on 1/19/2020
      Was referred to this for constipation by my doctor and it didn't help at all. Cannot take on an empty stomach. Even with food it upset my stomach some of the time. Strong after effects of the ginger.

      Pros

      Natural

      Cons

      Didn't work and so much ginger that you could taste it a while after taking it.
    • Will buy again

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      from Pennsylvania on 9/20/2019
      I’ve had so many digestive issues, and I truly feel a difference using this product.

      Pros

      I feel a difference with my gut motility.

      Cons

      It is too expensive
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Motility Champion

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      from Ooltewah TN on 8/29/2019
      This product helps me fight my motility battle daily. I highly recommend this product if you are dealing with this issue!
      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Helped child's FM and SIBO

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      from Youngsville LA on 8/23/2019
      This has been a lifesaver for my daughters constipation issues

      Pros

      Helps digestive system-no side effects-no diarrhea-

      Cons

      n/a
      review-checkI would recommend this item to a friend.
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Please ask any questions you may have about this specific product in the field below.

Your question(s) and our corresponding answer(s) will not be confidential and will be posted publically on this specific product page.

Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.

If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008

If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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