- MFG # 00925
- UPC # 737870925125
Benfotiamine‚ a fat-soluble form of vitamin B1 (thiamine)‚ supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress. For example‚ the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes‚ transketolase requires a co-factor. In this case‚ it needs assistance from thiamine. Unfortunately‚ thiamine is water-soluble‚ which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.
In a landmark study‚ benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%‚ compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage.46 Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB)‚ which is implicated in numerous inflammatory conditions.
Overall‚ benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. It can also reduce formation of advanced glycation end products to prevent glucose toxicity and correct endothelial cell defects caused by high concentrations of blood glucose‚ especially inside endothelial‚ retinal‚ kidney and nerve cells. Benfotiamine also helps maintain healthy endothelial function.
For those who desire to take higher doses of benfotiamine‚ Life Extension offers these 250-mg capsules.These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size 1 Vegetarian capsule
Servings Per Container 120
Amount Per Serving % Daily Value
Thiamine (vitamin B1) (as thiamine HCl) 10 mg 667%
Benfotiamine 250 mg **
Other ingredients: vegetable cellulose (capsule)‚ microcrystalline cellulose‚ dicalcium phosphate‚ rice flour‚ vegetable stearate‚ silica.
Take one to four capsule(s) daily with or without food‚ or as recommended by a healthcare practitioner.
Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements‚ please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Store tightly closed in a cool‚ dry place.
Benfotiamine is the fat soluble form of vitamin B1 clinically tested to offer protection against advanced glycation end products‚ typically associated with aging.
Allergy / Dietary Needs
- Vegetarian Capsules
Ratings & ReviewsReview This Item
Overall Rating for Mega Benfotiamine 250 mg - 120 Vegetarian Capsules
By Steve Martin
from Globe, Arizona
Stop the Tingling
I developed diabetes, doctor said Mega Benfotiamine by Life Extension would take away the nerve damage. I have a shooting in my foot once or twice a day, gone from hundreds per day. Benfotiamine will help with people that have nerve damage, it repairs. You don't have to have diabetes, just nerve pain in your extremities. Thanks Life Extension for a great product...
Simple, it WORKS. Reasonable price. Easy ordering.
Not a thing.....
√ I would recommend this item to a friend.
Questions About This ItemAsk a Question
Please ask any questions you may have about this specific product in the field below.
Your question(s) and our corresponding answer(s) will not be confidential and will be posted publically on this specific product page.
Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.
If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008
If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.Please log in to submit a question log in