- MFG # JVP
- UPC # 074306800084
New and Improved!
Comprehensive rebuilding formula.
Daily Maintenance of Healthy Joints.
Joint Vibrance provides cartilage-building cells called chondrocytes with the proper nutrients necessary for construction of new cartilage and synthesis of hyaluronic acid. It is the most comprehensive formula to nutritionally support healthy joint function. The entire formula is truly remarkable‚ and provides sound nutritional support for joint health.
Before we are born‚ chondrocytes work rapidly to build protection into our developing skeletons. Then we are born‚ grow‚ and age. The older we become‚ the slower chondrocytes work.
As chondrocyte activity flags over time‚ they eventually fail to adequately compensate for the daily wear and tear placed on joints by an active lifestyle. As a result‚ nearly everyone has some degree of cartilage breakdown by the age of 32 to 35. For centuries it was thought that the gradual deterioration made joint pain and loss of mobility an inevitable fact of aging.
Today’s science has shown us that the function of cartilage-building cells (chondrocytes) can be sustained as long as their nutritional requirements are met. Cartilage can indeed be brought back to greater levels of health‚ strengthened and thickened if proper nutrients are supplied.
There is one controlling principle in the effort to rebuild cartilage: There must be some cartilage with viable chondrocytes in the joint in order for repair to proceed. If prior joint surgeries have removed all cartilage‚ or if all cartilage in the joint has been worn completely away‚ then there would be no chondrocytes on site that could initiate the reconstruction process.
But most damaged joints do retain a good measure of cartilage. They can benefit from Joint Vibrance.
Version 4.0 Orange-Pineapple with Type 1 and Type 2 Collagen:
- Collagen Protein
- Hyaluronic Acid
- and so much more...
In Joint vibrance‚ two types of hydrolyzed collagen serve as the backbone of the formula. Human clinical trials have shown that after six weeks of consuming 7 to 10 grams of type 1 collagen‚ or 1 to 2 grams of type 2 collagen‚ new cartilage could be detected by x-ray examination of the joints. Joint Vibrance version 4.0 supplies both type 2 and type 1 collagen.
To understand why they are so important‚ you must understand that cartilage is made up of a mass of collagen fibers held together in a proteoglycan matrix or glue. (That glue is primarily synthesized from chondroitin sulfate A.) The collagen in cartilage – type 2 collagen – is slightly different in its composition than type 1 collagen found in bone‚ skin‚ tendon‚ blood vessel walls‚ and organs.
Supplemental type 2 collagen directly benefits cartilage synthesis. Type 1 collagen aids the synthesis of cartilage‚ supports bone health‚ and supports the integrity of tendons.
Cartilage deterioration is often accompanied by bone deterioration. Since bone is composed of 30% to 36% type 1 collagen‚ it makes sense to provide nutritional support not only to cartilage but also to bone in a dietary supplement targeted for joint health. Tendons also rely on type 1 collagen for health. The type 1 collagen in Joint Vibrance will help maintain the integrity of the stabilizing tendons wrapped across joints. Joint Vibrance then‚ does not just seek to build cartilage‚ but expands past that role to improve the health of all components of the joint.
CSA & Glucosamine & Hyaluronic acid:
Chondroitin sulfate A‚ with a little help from the other glycosaminoglycans in Joint Vibrance‚ is fashioned by chondrocytes into the sticky protein-sugar (proteoglycan) matrix‚ or glue‚ that holds all the collagen fibers together to form cartilage.
Glucosamine‚ a popular supplement for joint health‚ is converted to hyaluronic acid by chondrocytes. Each molecule of hyaluronic acid contains 5 molecules of water‚ giving it a very large‚ slippery structure. Its goal is to escape the chondrocyte where it was made‚ and slowly work its way out through the cartilage to take its place in synovial fluid. Along the way‚ the glucosamine that has now become hyaluronic acid acts to rehydrate cartilage‚ giving it greater cushioning power. In addition‚ Joint Vibrance delivers 264 mg of natural hyaluronic acid from chicken sternum. This is intended to support and replenish the hyaluronic acid content of synovial fluids in every joint.
But it takes more than glucosamine‚ chondroitin and hyaluronic acid to provide first class nutritional support to chondrocytes.
Silica from horsetail contributes the element silicon to connective tissue‚ giving them strength and stability. It is found in precisely the tissues we are discussing here: bone‚ cartilage‚ and tendons (as well as skin and blood vessels) helping to make them strong.
Antioxidants and anti-inflammatories:
Inflammation in sore‚ aching joints is characterized by oxidative damage to cells in the affected area. White blood cells (leucocytes) and macrophages‚ immune cells that travel through tissues looking for damage to clean up‚ utilize free radicals to dismantle the cellular debris they ingest as part of their cleanup work. Free radicals‚ inadvertently released during the process‚ run amok‚ inflicting some damage to healthy tissue surrounding the original site of injury. Antioxidants and anti-inflammatory agents can help control these biochemical events.
Grape seed extract‚ Curcuminoids‚ ApresFlex® Boswellia serrata extract and bromelain extracted from pineapple stems‚ as part of the Joint Vibrance formula‚ are intended to corral and quench the free radicals that participate in joint inflammation. Grape seed extract also helps bind broken collagen fibers in connective tissues (e.g. ligaments‚ tendons‚ skin etc.)
ApresFlex® concentrates AKBA‚ the acronym for 3-O-Acetyl-11-keto-beta-boswellic acid. AKBA is the most active compound of Boswellia serrata extracts. In the biochemical cascade that creates inflammation at the cellular level‚ AKBA is a potent inhibitor of the enzyme‚ 5-lipoxygenase (5-LOX). 5-LOX is a key enzyme in the synthesis of inflammatory cell messengers (leukotrienes) that are made from the ubiquitous omega-6 fatty acid‚ arachidonic acid. The dose of ApresFlex® required to quell the manufacture of inflammatory leukotrienes is just 100 mg. That is what you will find in each serving of Joint Vibrance 4.0.
But Joint Vibrance does not stop there. It contains a full gram of methyl sulfonyl methane‚ or MSM. This ingredient supports the re-synthesis of flexible disulfide bonds in connective tissue‚ including tendons and ligaments of the joint. The goal is to support overall flexibility and ease of movement.
Disulfide bonds work like hinges in a door. They contain two sulfur molecules‚ and predominate in the connective tissue of infants‚ and children. Those disulfide bonds tend to be replaced by stiffer‚ protein bonds as we age. It has been suggested that the replacement of disulfide bonds by protein bonds is due to a chronic‚ subclinical deficiency of sulfur throughout our lifetimes. Whether or not that is true‚ we do know that supplementing the diet with MSM can help increase again the number of flexible disulfide bonds in connective tissue.
Minerals and enzymes:
In order for new synthesis of cartilage to take place within chondrocytes‚ certain enzymes are required. You can look at enzymes as miniature carpenters. These are the agents within cells that catalyze the chemical reactions that build tissue and keep us alive. An enzyme is made up of three primary components. One is a protein fraction; another is a vitamin or vitamin metabolite; and the last essential component is a mineral. As soon as the mineral takes its place‚ the enzyme comes alive and can do its work. It is somewhat like sticking the key into a car's ignition‚ and giving it a turn.
Joint Vibrance includes a selection of minerals that are known to be required by the chondrocytes’ enzymes responsible for cartilage synthesis. This helps assure that enzymes can be synthesized within the chondrocytes when they are needed‚ and then get to work on schedule to build new cartilage.
Cartilage-building chondrocytes are lodged deep inside cartilage which is hidden away behind a protective synovial membrane inside the ligaments that bind the joint together. Wrapped over the joint are muscles and their tendons‚ providing extra stability. Although chondrocytes never lose the ability to do their job‚ nutrients reach them only by slow‚ passive diffusion through the synovial membrane and into synovial fluid lubricating the joint. That is why it is important to use Joint Vibrance daily‚ causing a steady‚ regular flow of nutrients to the ends of the capillaries that end at the barrier of the synovial membrane.
As we said at the start‚ no other joint health formula is as complete as Joint Vibrance.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size: 1 Scoop (17.7 g)
Servings Per Container:21
Amount Per Serving / % DV
Calories from Fat 6
Total Fat 0.7 g / 1 %
Total Carbohydrate 5.5 g / 2 %
Dietary Fiber 3.2 g / 13 %
Protein 10 g / 22 %
Vitamin C (ascorbic acid) 100 mg / 167 %
Calcium (from lactate) 150 mg / 15 %
Iron 1 mg / 6 %
magnesium (from lactate) 50 mg / 13 %
Zinc (from citrate) 5 mg / 250 %
Manganese (from citrate) 5 mg / 2 %
Sodium 53 mg / 2 %
Potassium 200 mg / 6 %
Type 1 collagen (Bovine) 8‚600 mg / **
Type 2 collagen (Avian) 1‚500 mg / **
Glucosamine HCL (Crustacean) 1‚500 mg / **
Chondroitin sulfate A (Avian & Bovine) 1‚000 mg / **
Hyaluronic acid (Avian) 264 mg / **
Other glycosaminoglycans (Avian & Bovine) 120 mg / **
Silica‚ from Horsetail 3 mg / **
Boron (1 mg as glycinate; 2 mg as Ca-fructoborate) 3 mg / **
MSM (Methylsulfonylmethane) 1‚000 mg / **
ApresFlex® (Boswellia serrata extract) 100 mg / **
Curcuminoids (Turmeric root extract‚ 95%) 100 mg / **
Bromelain (pineapple stem; NLT 2‚400 GDU/g) 100 mg / **
Grape seed standardized extract (95% polyphenols‚ 90% proanthocyanidins) 25 mg / **
Palatability and Solubility Factors
Natural Orange-pineapple flavor 646 mg / **
Citric acid 534 mg / **
Sunflower lecithin powder 100 mg / **
Stevia extract 70 mg / **
**Daily Value not established.
Once a day as a dietary supplement‚ mix 1 scoop (enclosed) of Joint Vibrance into 4 to 8 oz. of water‚ diluted fruit juice or your beverage of choice. Stir briskly or blend in a shaker bottle. Best taken between meals to maximize absorption of nutrients.
In Water: Mix one scoop into 8 ounces of cool water‚ adding a squeeze of fresh lemon for extra zest.
In Juice: The orange/pineapple flavor of Joint Vibrance works well in juice. To reduce calories‚ try diluting the juice 50% with water.
In a Smoothie:
- 1 Scoop of Joint Vibrance.
- 8 oz. orange juice.
- 1/2 cup fresh or frozen mango pieces
- 1/3 of a fresh banana
- 2 ice cubes
- Blend and Enjoy!
Keep out of reach of children. Use this product as a dietary supplement only. Do not use for weight reduction. Store joint vibrance in a cool‚ dry place.
Allergy / Dietary Needs
- Gluten Free
- Made in the USA
Ratings & ReviewsReview This Item Be the first to review this item.
Questions About This ItemAsk a Question
Please ask any questions you may have about this specific product in the field below.
Your question(s) and our corresponding answer(s) will not be confidential and will be posted publically on this specific product page.
Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.
If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008
If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.Please log in to submit a question log in