- MFG # V931
- UPC # 693749099314
CurcuVET is a unique curcumin extract that is significantly better absorbed than other curcumin extracts. Whether taken as a supplement or from food‚ curcumin is generally poorly absorbed into the bloodstream. Scientists at Indena S.p.A.‚ the worldwide experts in botanical extract technology‚ have uncovered the key to curcumin absorption – phytosome technology. Phytosomes are plant extracts bound to a phospholipid‚ in this case phosphatidylcholine (PC)‚ an essential component of cell membranes. When taken orally‚ PC is very well absorbed. By attaching a curcumin molecule to a PC molecule‚ the PC ushers the curcumin across the cell membrane for superior absorption.
Studies demonstrate CurcuVET supports a healthy inflammatory response in small animals and horses. A recent European study analyzed the bioactivity of CurcuVET compared to non-steroidal anti-inflammatory drugs and found their bioactivity was similar. The study's sponsors‚ who were studying canine arthritis‚ found CurcuVET was effective in down-regulating the pro-inflammatory substances‚ tumor necrosis factor-alpha (TNF-α) and nuclear factor-kappaB (NF-κB).
A similar equine study on the effect of CurcuVET on cytokine gene expression found significant down-regulation of interleukin (IL)-1β and IL-1RN in mares and inhibition of cyclooxygenase-2‚ TNF-α‚ and IL-1RN and increase in IL-6 in foals.
Similar results were achieved in an eight-month human trial of Meriva. Enhanced joint health was reflected in improvements in both clinical and biochemical end points.
A 2007 study published in the journal‚ Cancer Chemotherapy and Pharmacology‚ demonstrated the superior bioavailability of curcumin phytosome (as Meriva®‚ the CurcuVET equivalent for humans) compared to ordinary curcumin. Liver levels of curcumin were also higher with this supplementation. In a more recent‚ randomized‚ single-blind‚ crossover study in nine humans‚ total curcuminoid bioavailability as evaluated by the plasma area under the curve (AUC) was about 29-fold higher for Meriva than for the conventional turmeric extract.
Curcumin has demonstrated its potential to help maintain the animal's normal inflammatory response. In numerous animal studies‚ curcumin has shown the ability to help maintain healthy intestinal mucosa under various adverse conditions. Among the effects noted in the various trials have been decreased nuclear factor-kappaB‚ nitric oxide‚ and free radicals in the colonic mucosa. For example‚ a small human pilot study on patients who had poor gastrointestinal health demonstrated that the administration of curcumin improved overall well-being‚ maintained the levels of biomarkers generally associated with the body's normal inflammatory response‚ and served as a non-drug adjunct that did not disrupt the use of conventional medications.
Several studies have illustrated curcumin's hepatoprotective effects‚ leading researchers to suggest its use can protect the liver from exogenous insults from environmental toxins. Curcumin also has the capacity to increase both the flow and solubility of bile. Curcumin's hepatoprotective effects are due in part to direct free radical scavenging; but curcumin also enhances the animal's natural antioxidant system‚ which increases glutathione levels‚ thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.
A recent European canine study found CurcuVET was effective in helping to maintain the balance of markers associated with a normal inflammatory response.
In a similar equine study‚ the effect of CurcuVET on mares and foals was found to have a positive impact on maintaining normal inflammatory responses.
A recent human clinical study demonstrated that in more than 80 percent of patients with a long-term condition known to adversely affect ocular health‚ Meriva (the human equivalent of CurcuVET) was well tolerated‚ reduced symptoms of eye discomfort‚ improved overall quality of life‚ and helped maintain the eye's normal inflammatory response.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Active Ingredients Per Capsule: 50mg
Curcumin Phytosome (Curcuma longa extract (root) / Phosphatidylcholine complex) (CurcuVET®)
Inactive Ingredients: Hypromellose (derived from cellulose) capsule‚ microcrystalline cellulose‚ silicon dioxide.
Cats: 1/2-1 capsule daily.
Dogs: 1-3 capsules per 25 lbs body weight daily.
Safe use in pregnant animals or animals intended for breeding has not been proven. Safety during nursing has not been proven. Potential drug interactions. Do not use in high doses with anticoagulant drugs or patients with stomach ulcers. If animals condition worsens or does not improve‚ stop product administration and consult your veterinarian. May be GI irritant. For use in dogs only. Keep out of the reach of children and animals. In case of accidental overdose‚ contact a health professional immediately.
Ratings & ReviewsReview This Item
Overall Rating for CurcuVET-SA50 90 Capsules
A great alternative to NSAIDS
My cat has Probable IBD and allergies. Thorne makes great animal supplements as well as for people. My cat has been taking this supplement now for over 2 months and has done well on it. With allergies in mind I do switch out the capsule for another one that is a plain gelatin capsule (size 00 by Now brands) and administer it to him via mouth. I have not tried putting it in his Hypoallergenic canned food as he is picky and I dont feel he would readily eat it. I really believe this supplement has helped with the inflammatory process of his IBD and get a double bonus from it since it protects the liver and kidneys. A relatively safe supplement with no side effects noted after two months. I did start out for two weeks only giving half a capsule to make sure he would be able to tolerate it and look for any allergic reactions. He is now taking the full dose once a day.
great alternative to prescription NSAIDS
great for any inflammatory condition
√ I would recommend this item to a friend.
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