- MFG # N/A
- UPC # 036733008211
Angiogenesis involves a complex cascade of events that results in the growth of new blood vessels from existing microvascular structures. The process of angiogenesis is absolutely necessary for growth and development. This means that any inhibitors of angiogenesis should be avoided in childhood‚ pregnancy or circumstances where patent blood vessels or neovascularization is obligatory. Inhibition of new blood vessel growth may cause fetal malformations. New blood vessel growth (angiogenesis) is a normal body function e.g. wound repair.
Blood vessel structures are controlled by a balancing act that involves growth factors‚ which promote angiogenesis and factors that inhibit angiogenesis. Therefore‚ it is somewhat naïve to think about simple angiogenic promotion or inhibition‚ because these processes are subject to modulation by a variety of different biological response modifiers. One may understand the limitations of the use of “single agents” that may inhibit angiogenesis‚ such as shark cartilage or its extracts.
The role of the modification of angiogenesis has been pioneered by Moses Judah Folkam MD. While angiogenesis plays a pivotal role in normal events such as wound healing‚ menstruation and fetal development‚ there are many disorders that result from disturbed angiogenesis. These angiogenic-dependent circumstances include diabetic retinopathy‚ psoriasis‚ arthritis and cancer. The role of angiogenesis in the promotion of tumor growth‚ cancer progression‚ proliferation and metastatic spread of cancer have been widely researched. These are drug treatment approaches to antiangiogenesis and such claims cannot be made for dietary supplements.
There are many different types of natural angiogenesis inhibitors with varying toxicity. The complexities of the process of angiogenesis results predictably in the existence of many different substances with different targets of action on the complex cascade of events. While many natural substances‚ that can be used in dietary supplements‚ are known to exert varying degrees of antiangiogenic effects‚ it is not possible to make claims about natural angiogenesis modulation in disease treatment (variable evidence).
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size: 6 Capsules
Servings per Container: 30
Amount per Serving/% RDI
Bovine Cartilage 1000 mg/**
Chitin 500 mg/**
N-Acetyl-Glucosamine 500 mg/**
Chicken Cartilage 250 mg/**
Sea Cucumber 200 mg/**
Quercetin Dihydrate 200 mg/**
Garlic 100 mg/**
Green Tea 95% Polyphenols 100 mg/**
Papain 100 mg/**
Aloe Vera 200:1 Extract 50 mg/**
Ellagic Acid (From Pomegranate) 50 mg/**
Grape Seed Extract (95% OPC) 50 mg/**
Soy Isoflavones 30 mg/**
Magnolia Bark Extract (1.5 Honokiol) 20 mg/**
Pine Bark Extract (85% Proanthocyanidins) 10 mg/**
Vitamin A* 10‚000 IU/**
Vitamin D-3* 800 IU/**
**RDI not established for other ingredients.
Other Ingredients: Gelatin‚ Cellulose and Magnesium.
Take two capsules three times daily with 4 oz. of pure water.
Not for use in pregnancy or childhood.
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Joy Perry on 5/19/2015
Might there be any side effects from this such as extra tiredness?A
PureFormulas on 5/21/2015
Joy, the side affects are not listed. We ask that you please speak with your health care provider about what the possible side affects may be.
- PureFormulas on 5/21/2015