- MFG # 00920
- UPC # 737870920120
Benfotiamine‚ a fat-soluble form of vitamin B1 (thiamine)‚ supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress. For example‚ the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes‚ transketolase requires a co-factor. In this case‚ it needs assistance from thiamine. Unfortunately‚ thiamine is water-soluble‚ which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.
In a landmark study‚ benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%‚ compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage. Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB)‚ which is implicated in numerous inflammatory conditions.
Overall‚ benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. It can also reduce formation of advanced glycation end products to prevent glucose toxicity and correct endothelial cell defects caused by high concentrations of blood glucose‚ especially inside endothelial‚ retinal‚ kidney and nerve cells. Benfotiamine also helps maintain healthy endothelial function.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size 1 vegetarian capsule
Servings Per Container 120
Amount Per Serving % Daily Value
Thiamine (vitamin B1) (as thiamine HCl) 25 mg 1667%
Benfotiamine 100 mg **
**Daily Value not established.
Other ingredients: microcrystalline cellulose‚ vegetable cellulose (capsule)‚ silica‚ vegetable stearate.
Take one capsule four times daily with or without food‚ or as recommended by a healthcare practitioner.
If using Mitochondrial Energy Optimizer or Super Carnosine‚ only two to three capsules daily are needed to reach the optimal dose of 400 mg daily.
Do not exceed recommended dose. Keep out of reach of children. Do not purchase if outer seal is broken or damaged.
Store tightly closed in a cool‚ dry place.
When using nutritional supplements‚ please consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Allergy / Dietary Needs
- Vegetarian Product
Ratings & ReviewsReview This Item Be the first to review this item.
Questions About This ItemAsk a Question
Please ask any questions you may have about this specific product in the field below.
Your question(s) and our corresponding answer(s) will not be confidential and will be posted publically on this specific product page.
Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.
If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008