Thorne   5-MTHF 15 mg - 30 Capsules

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"healthy supplement for overall health"  Read all reviews

Item Number: TR1419
Serving Size: 1 Capsule Servings per Container: 30
Price per Serving:  $2.07 Price per Unit*: $2.07 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
39 In Stock.

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Active folate for mood‚ heart health‚ and nerve support*

5-MTHF is an active‚ tissue-ready form of folate.* It's an essential B vitamin that supports methylation.* Many individuals don't get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic makeup.

Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate)‚ the active form of folic acid‚ because they have intestinal or liver dysfunction‚ or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects‚ which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin‚ melatonin‚ dopamine‚ epinephrine‚ and norepinephrine‚ supplementation supports healthy mood.

Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner.

It is important for a woman of childbearing age to get enough folic acid – not just those women who are planning to become pregnant. Because half of pregnancies are unplanned‚ any woman who could become pregnant should get enough folic acid every day. Folic acid intake is especially important before conception and during early pregnancy‚ since its biggest need is during the first trimester – when a woman might not even know she is pregnant. Supplementation with the active form of folic acid – 5-MTHF (L-5 Methyltetrahydrofolate)– is always preferable.

Acting with vitamin B12‚ 5-MTHF functions as a methyl-group donor‚ thereby facilitating the conversion of the amino acid homocysteine to methionine. An elevated homocysteine level is a risk factor for a number of undesirable health conditions. Methyl-group donation is vital to many biochemical conversion processes‚ including the synthesis of serotonin‚ melatonin‚ and DNA.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # B133
  • UPC # 693749006626
Official Website:

Serving Size: One Capsule
Servings Per Container: 30

One Capsule Contains: / %DV

Folate (15 mg as L-5-Methyltetrahydrofolate†) 25 mg DFE / 6‚250%

Daily Value (DV)

Other Ingredients: Microcrystalline Cellulose‚ Hypromellose (derived from cellulose) capsule‚ Leucine‚ Silicon Dioxide.

†This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolate (Extrafolate-S®). Extrafolate-S is a registered trademark of Gnosis S.p.A.

Gluten Free.

Take 1 capsule daily. This product is intended for use under the guidance of a health-care practitioner.

TAMPER EVIDENT: Use only if bottle is sealed. Store tightly sealed in a cool‚ dry place.

If pregnant‚ consult your health-care practitioner before using this product.

  • Egg Free
  • Gluten Free
  • High Fructose Corn Syrup Free
  • Nut Free
  • Peanut Free

Ratings and Reviews

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  • 5.0
5 2
  • 2 Reviews
    • Verified Buyer


      from Los Angeles CA on 7/20/2020
      healthy supplement for overall health


      works effectively and has quality ingredients


      review-checkI would recommend this item to a friend.
    • Verified Buyer

      Amazing Formula 5-MTHF

      from Westland MI on 6/26/2020
      I've had mild depression for most of my life. My Dr had me on a standard drug that never seemed to help much. One day my Homeopathic Dr put me on the above drug without telling me what it was for. I trust this Dr and decided to take it, not really knowing what it was for. About two months later, I noticed that i wasn't depressed any more. I mean not even a little. I have been on it for a year now and I have no depression at all. It's gone. This is a miracle medicine for me.


      Everything. I know I'll feel just fine on it. I hope I can take it forever.


      It's a little expensive for a retiree on Medicare.
      review-checkI would recommend this item to a friend.

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If you have any general questions regarding orders or our policies and programs, please contact our Customer Happiness Team @ 1.800.383.6008

If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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