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If it’s backordered, we’ll notify you by email and will ship it when it’s available (usually 1 week or less).
VSL#3 Capsules is a probiotic medical food for the dietary management of Irritable Bowel Syndrome and Ulcerative Colitis consisting of 8 strains of live freeze-dried lactic acid bacteria. VSL #3 Capsules are available in a 60 count bottle. Each 2 capsule serving contains 225 billion live probiotic bacteria.
As a medical food‚ VSL#3® is specially formulated and processed to provide a precise mixture of certain bacterial species with potential synergistic relationships.
The importance of the gastrointestinal microflora in the normal functioning of the human gastrointestinal tract is well recognized. Several studies demonstrate that patients with IBS‚ UC‚ or an ileal pouch may have decreased luminal concentrations of lactobacilli and bifidobacteria compared with healthy individuals. Patients with IBS‚ UC‚ or an ileal pouch may benefit from consuming high levels of probiotic bacteria so as to maintain the appropriate quantity and balance of beneficial microflora in their gastrointestinal tract. This is particularly important for these patients in view of their frequent and often long-term antibiotic treatment and recent evidence implicating harmful intestinal bacteria in inflammatory bowel diseases. Hence‚ IBS‚ UC‚ and ileal pouch patients may have a distinct nutritional requirement that differs from normal individuals. Daily consumption of high levels of probiotic bacteria is needed to maintain adequate and balanced colonization in the gastrointestinal tract‚ and this cannot be achieved simply by modification of the normal diet.
VSL#3® is intended for use only by IBS‚ UC‚ or ileal pouch patients under the care of a physician.
VSL#3® has been the subject of extensive clinical research in the dietary management of IBS‚ UC‚ and an ileal pouch. In one study‚ the consumption of VSL#3® was associated with a 39% reduction in bloating in patients with diarrhea-predominant IBS. In the same study‚ fecal urgency scores showed a trend toward reduction vs. placebo. In a second study‚ the consumption of VSL#3® was associated with reduced flatulence (gas) by 25% vs. placebo. In both IBS studies‚ the consumption of VSL#3® was well tolerated with no adverse events reported.
Several published studies have suggested that daily ingestion of VSL#3® can aid in the dietary management of UC. A recent study concluded that 77% of the patients consuming VSL#3® in the dietary management of active UC had a positive response to the product with no adverse events. In a study with VSL# 3® in dietary management of UC patients intolerant or allergic to 5-ASA‚ 75% of patients had a positive response to the product for 12 months.
Three double blind‚ placebo controlled trials have been published which show that VSL#3® aids in the dietary management of pouchitis. VSL#3® is the only probiotic recognized as an effective tool for the dietary management of pouchitis by the American College of Gastroenterology and the German Association of Gastroenterology.
Probiotics have generally been associated with a long history of safe use. In fact‚ many probiotic species are integral to the production of fermented foods and have been consumed safely as part of these foods for millennia. Furthermore‚many bifidobacteria and lactobacilli species are normal‚ nonpathogenic inhabitants of the human gastrointestinal tract‚ oral cavity‚ skin‚ and vagina. While‚ theoretically‚ probiotic species could act as opportunistic pathogens‚ epidemiological surveillance data indicate that the risk of infection from consumption of lactobacilli is negligible. In the available literature‚ documented cases of infection attributable to probiotic treatment are rare and limited to case reports. These case reports are primarily associated with patients having compromised immune systems or other major health problems. Each strain of probiotic bacteria in VSL#3® is non pathogenic and non toxigenic.
Studies of VSL#3® have been conducted in several animal models of colitis and inflammatory liver disease. In experimental animal models of colitis‚ there are serious derangements in epithelial permeability and barrier function‚ causing the animals to be particularly vulnerable to bacterial translocation and inflammatory immune responses. Collectively‚ these studies demonstrate that VSL#3® may normalize gut permeability and barrier function and that it is associated with beneficial anti-inflammatory and immunomodulatory properties. The probiotics contained within VSL#3® do not translocate from the gut lumen or act opportunistically when ingested by animals suffering from colitis.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Ingredients: VSL#3 Capsules contain one strain of streptococcus thermophilus‚ three strains of bifidobacterium and four strains of lactobacillus in defined ratios. Inactive ingredients: microcrystalline cellulose‚ stearic acid‚ magnesium stearate‚ vegetable capsule (hydroxypropyl methycellulose)‚ and silicon dioxide.
Some dairy ingredients are used in the culturemedium but are removed during manufacturing. There might be trace amounts at very low levels. For this reason VSL#3® is not defined as a dairy-free product but as a non- dairy product.
Kosher and Halal certified.
Consume 2-8 capsules daily or as directed by your physician. Adjustment of the intestinal flora can take a few days or weeks; it may take up to one month for the colonization of the gut to become optimally stable.
For Dietary Management of Irritable Bowel syndrome: 2-4 capsules per day (225-450 billion).
For Dietary Management of Ulcerative Colitis: 4-8 capsules per day (450-900 billion).
Please keep this product out of reach of children. Pregnant or lactating women should consult with a physician or healthcare professional before using this or any other medical food product.
Drug Interactions: Avoid taking with antibiotics. Some antibiotics may inactivate certain strains of bacterium in VSL#3®.
Side Effects: Mild abdominal bloating has been reported in the first fewdays of consuming VSL#3®.
VSL#3® Capsules should be refrigerated (39-46°F‚ 4-8°C). If stored under refrigeration‚ the product is guaranteed through “Best if used by” date.
VSL#3® Capsules can be stored at room temperature for up to one week without adversely affecting potency of bacteria.
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Domestic orders placed by 5 PM Eastern Time will be packed and shipped the same day, pending verification of billing information and the shipping method selected. Orders containing out-of-stock items or refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
Excludes all orders placed during weekends and on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year’s Day).