Domestic orders placed by 5 PM Eastern Time will be packed and shipped the
same day, pending verification of billing information and the shipping
Orders containing refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
If an item on your order is on backorder we will notify you by email
and we will ship what we have in stock, the backordered item (s) will be
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Order before 5 p.m. EST and this item will ship out today. Except during weekends and holidays.
We’re fast like that. Place your order before 5 p.m. and it will ship the same day, as long as we can verify billing and shipping information. Refrigerated items will be processed quickly, but might not ship the same day.
If it’s backordered, we’ll notify you by email and will ship it when it’s available (usually 1 week or less).
VSL#3® is a probiotic medical food for the dietary management of Irritable Bowel Syndrome‚ Ulcerative Colitis‚ or an Ileal Pouch consisting of 8 strains of live freeze-dried lactic acid bacteria. Each sachet contains 450 billion live probiotic bacteria and is supplied in a box containing 30 sachets.
Proprietary Strains of Bacteria: - Streptococcus thermophilus. - Bifidobacterium breve. - Bifidobacterium longum*. - Bifidobacterium infanti*s. - Lactobacillus acidophilus. - Lactobacillus plantarum. - Lactobacillus paracasei. - Lactobacillus del brueckii subsp. bulgaricus. *Recently reclassified as B lactis.
As a medical food‚ VSL#3® is specially formulated and processed to provide a precise mixture of certain bacterial species with potential synergistic relationships.
The importance of the gastrointestinal microflora in the normal functioning of the human gastrointestinal tract is well recognized. Several studies demonstrate that patients with IBS‚ UC‚ or an ileal pouch may have decreased luminal concentrations of lactobacilli and bifidobacteria compared with healthy individuals. Patients with IBS‚ UC‚ or an ileal pouch may benefit from consuming high levels of probiotic bacteria so as to maintain the appropriate quantity and balance of beneficial microflora in their gastrointestinal tract. This is particularly important for these patients in view of their frequent and often long-term antibiotic treatment and recent evidence implicating harmful intestinal bacteria in inflammatory bowel diseases. Hence‚ IBS‚ UC‚ and ileal pouch patients may have a distinct nutritional requirement that differs from normal individuals. Daily consumption of high levels of probiotic bacteria is needed to maintain adequate and balanced colonization in the gastrointestinal tract‚ and this cannot be achieved simply by modification of the normal diet.
VSL#3® is intended for use only by IBS‚ UC‚ or ileal pouch patients under the care of a physician.
VSL#3® has been the subject of extensive clinical research in the dietary management of IBS‚ UC‚ and an ileal pouch. In one study‚ the consumption of VSL#3® was associated with a 39% reduction in bloating in patients with diarrhea-predominant IBS. In the same study‚ fecal urgency scores showed a trend toward reduction vs. placebo. In a second study‚ the consumption of VSL#3® was associated with reduced flatulence (gas) by 25% vs. placebo. In both IBS studies‚ the consumption of VSL#3® waswell toleratedwith no adverse events reported.
Several published studies have suggested that daily ingestion of VSL#3® can aid in the dietary management of UC. A recent study concluded that 77% of the patients consuming VSL#3® in the dietary management of active UC had a positive response to the productwith no adverse events. In a study with VSL#3® in dietary management of UC patients intolerant or allergic to 5-ASA‚ 75% of patients had a positive response to the product for 12 months.
Three double blind‚ placebo controlled trials have been published which show that VSL#3® aids in the dietary management of pouchitis. VSL#3® is the only probiotic recognized as an effective tool for the dietary management of pouchitis by the American College of Gastroenterology and the German Association of Gastroenterology.
Probiotics have generally been associated with a long history of safe use. In fact‚ many probiotic species are integral to the production of fermented foods and have been consumed safely as part of these foods for millennia. Furthermore‚many bifidobacteria and lactobacilli species are normal‚ nonpathogenic inhabitants of the human gastrointestinal tract‚ oral cavity‚ skin‚ and vagina. While‚ theoretically‚ probiotic species could act as opportunistic pathogens‚ epidemiological surveillance data indicate that the risk of infection from consumption of lactobacilli is negligible. In the available literature‚ documented cases of infection attributable to probiotic treatment are rare and limited to case reports. These case reports are primarily associated with patients having compromised immune systems or other major health problems. Each strain of probiotic bacteria in VSL#3® is non pathogenic and non toxigenic.
Studies of VSL#3® have been conducted in several animal models of colitis and inflammatory liver disease. In experimental animal models of colitis‚ there are serious derangements in epithelial permeability and barrier function‚ causing the animals to be particularly vulnerable to bacterial translocation and inflammatory immune responses. Collectively‚ these studies demonstrate that VSL#3® may normalize gut permeability and barrier function and that it is associated with beneficial anti-inflammatory and immunomodulatory properties. The probiotics contained within VSL#3® do not translocate from the gut lumen or act opportunistically when ingested by animals suffering from colitis.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Ingredients: VSL#3 contains one strain of streptococcus thermophilus‚ three strains of bifidobacterium and four strains of lactobacillus in defined ratios.
Inactive ingredients: Maltose‚ lemon flavoring‚ and silicon dioxide.
Some dairy ingredients are used in the culture medium but are removed during manufacturing. There might be trace amounts present at very low levels. For this reason VSL#3® is not defined as a dairy-free product but as a non- dairy product.
Kosher and Halal certified.
Consume ½- 8 sachets daily or as directed by your physician. Regular VSL#3® can be mixed into cold water or any cold‚ non-carbonated beverage and consumed‚ and has a light lemon cream flavor. Adjustment of the intestinal flora can take a few days or weeks; it may take up to one month for the colonization of the gut to become optimally stable.
For the Dietary Management of : - Irritable Bowel Syndrome 1/2 -1 sachets Per Day. - Ulcerative Colitis 1-2 sachets Per Day. - Pouchitis: 2-4 sachets Per Day. - Active Ulcerative Colitis 4-8 sachets Per Day.
1 sachet contains 450 Billion Bacteria.
Please keep this product out of reach of children. Pregnant or lactating women should consult with a physician or healthcare professional before using this or any other medical food product.
VSL#3® should be refrigerated (39-46°F‚ 4-8°C). If stored under refrigeration‚ the product is guaranteed through “Best if used by” date. VSL#3® can be stored at room temperature for up to one week without adversely affecting potency.
Avoid taking with antibiotics. Some antibiotics may inactivate certain strains of bacterium in VSL#3®.
Side Effects: Mild abdominal bloating has been reported in the first few days of consuming VSL#3®.
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Domestic orders placed by 5 PM Eastern Time will be packed and shipped the same day, pending verification of billing information and the shipping method selected. Orders containing out-of-stock items or refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
Excludes all orders placed during weekends and on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year’s Day).