- MFG # 2802F
- UPC # NW1334
SAM-e is the abbreviated name for a natural substance called S-adenosyl methionine. SAMe is present in all cells of the body and is crucial in maintaining proper methylation-one of the most important biochemical reactions in the entire body. SAM-e is considered to be primary methyl donor‚ meaning that it can donate methyl groups (one-carbon molecules) to inactive compounds and thereby biologically activate them. This is extremely important for maintaining and accelerating many pathways‚ especially brain neurotransmitters‚ detoxification‚ DNA synthesis‚ immune system activity and joint health. Methylation promotes healthy cells‚ regulates the expression of genes (including cancer suppressor genes)‚ and helps with the synthesis of various hormones and neurotransmitters‚ including serotonin‚ melatonin‚ dopamine and adrenaline.
SAM-e is used for psychiatric illnesses‚ infertility‚ liver concerns‚ premenstrual disorders and musculoskeletal disorders‚ among others. SAM-e has been studied extensively in the treatment of osteoarthritis and depression. Many trials provide evidence that SAM-e reduces the pain associated and osteoarthritis and is well tolerated in this patient population.. Anti-inflammatory and analgesic (pain relieving) activity has also been attributed to SAM-e.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size: 1 Tablet
Amount Per Serving / % DV
Proprietary Blend 200mg* of: S-Adenosyl Methionine (SAMe)
*Daily Value (DV) not established.
Other Ingredients: DiCalcium Phosphate‚ Microcrysyalline Cellulose‚ Vegetable Stearine‚ Stearic Acid‚ Magnesium Stearate.
Use as directed by a healthcare professional.
Side effects are uncommon‚ but occasionally gastrointestinal upset and anxiety can occur. There are no confirmed drug interactions with SAM-e‚ but caution is advised with the use of antidepressants‚ including serotonin re-uptake inhibitors and MAO inhibitors‚ due to potentially enhanced serotonin. Some recommended avoiding SAM-e for individuals with bipolar disorder or manic depression.