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Order before 5 p.m. EST and this item will ship out today. Except during weekends and holidays.
We’re fast like that. Place your order before 5 p.m. and it will ship the same day, as long as we can verify billing and shipping information. Refrigerated items will be processed quickly, but might not ship the same day.
If it’s backordered, we’ll notify you by email and will ship it when it’s available (usually 1 week or less).
One tablet of SALIZAIN provides 240 mg of salicin, which is the active ingredient in white willow bark. A andomized controlled study compared 240 mg of salicin to 12.5 mg of Vioxx, a OX2 inhbitor. At four weeks of treatment in 228 patients with idiopathic low back pain, reduction of pain was equal in both groups 1 In a randomized double-blind study, patients with low back pain exacerbations received either 240 mg of salicin, 120 mg of salicin, or placebo. In the last week of treatment, 39% of patients receiving 240 mg were pain-free compared to 21% who received 120 mg and 6% taking the placebo.
Recently, the American College of Physicians and the American Pain Society developed clinical guidelines for the treatment of low back pain. White willow bark was deemed to be moderately beneficial for treatment of acute low back pain, which was the same rating as acetaminophen, NSAIDS, muscle relaxants, and opiates.
In a randomized placebo-controlled double-blind trial in patients suffering from osteoarthritis of the hip or knee, subjects received either 240 mg of salicin or placebo daily for two weeks. At the end of two weeks, subjects receiving salicin reported a 14% reduction in pain compared to a 2% increase in those receiving placebo.
The effectiveness of salicin in relieving minor pains should be considered in the context of cost and side effects. The patient cost for Salizain is only $24.00 per month, which is substantially less then the cost for COX2 inhibitors such as Celebrex.
The active ingredient in white willow bark is salicin and it is converted to salicylic acid after absorption, which is thought to be a reason why there are minimal side-effects compared to aspirin and traditional NSAIDs. In placebo-controlled studies, there were 20 adverse events in the 179 white willow bark patients compared to 35 events in 109 placebo patients. The low incidence of adverse events observed in multiple studies suggests that willow bark extract may be an effective alternative, especially in patients who cannot tolerate NSAIDs.
As white willow bark has additional components, it is thought that the observed analgesic effect of willow bark may therefore not be attributed to salicylic acid alone. It can be speculated that other constituents of willow bark (e.g. tannins, flavonoids, salicin, salicin esters or others) may contribute to the overall effect.
Not well known is that fruits and vegetables contain salicylates, which highlights the importance of making appropriate dietary modifications for any patient in need of pain relief. Vegetable and fruit intake at a level consumed by vegetarians provides a level of dietary salicylates that appears to be equivalent to 75 mg of aspirin. In summary, according to the available research, white willow bark should be viewed as a natural analgesic agent for the treatment of minor pains.
In conjunction with a diet rich in fruits and vegetables, the use of white willow bark may provide the best available natural approach for modulating acute pain.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size 1 Tablet Servings Per Container 30
Amount Per Serving % Daily Value
Salicin (from 979.2 mg white willow bark extract) 240 mg
*Daily Value not established
Allergy Information - Product Details
Only one tablet daily as opposed to 2 or more for the previous formulation (improved patient compliance).
Consult your healthcare professional.
Salizain 30 Vegetarian Tablets
4.5 Stars based on 3 Review(s)
I would recommend this item to a friend.
January 25, 2013
Salizain has a reasonable price and it relieves the aches and pains I experience in my joints and lower back.
I would recommend this item to a friend.
Used this for knee pain
January 10, 2013
I used Salizain along with the Pro-Enz formula for a twisted knee and it helped greatly to allieviate the deep muscular ache. It also helps with my headaches; although it take a bit longer to work than Excedrin.
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Domestic orders placed by 5 PM Eastern Time will be packed and shipped the same day, pending verification of billing information and the shipping method selected. Orders containing out-of-stock items or refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
Excludes all orders placed during weekends and on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year’s Day).