Domestic orders placed by 5 PM Eastern Time will be packed and shipped the
same day, pending verification of billing information and the shipping
Orders containing refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
If an item on your order is on backorder we will notify you by email
and we will ship what we have in stock, the backordered item (s) will be
shipped as soon as it is back in stock (usually within 1 week or less)
Excludes all orders placed during weekends and on major US holidays(Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day)
Order status and tracking information is updated
1 business day or less after the order is placed . You can now get real-time
status on your PureFormulas order on your cellphone or online.
Track your order
Order before 5 p.m. EST and this item will ship out today. Except during weekends and holidays.
We’re fast like that. Place your order before 5 p.m. and it will ship the same day, as long as we can verify billing and shipping information. Refrigerated items will be processed quickly, but might not ship the same day.
If it’s backordered, we’ll notify you by email and will ship it when it’s available (usually 1 week or less).
Nutritionally Supports Relaxation and Sound Sleep!
Melatonin is a natural lipophilic hormone secreted by the pineal gland in the brain‚ and is classified as an indoleamine. Closely involved in the natural sleep cycle‚ Melatonin can help support restful sleep patterns. Melatonin may be appropriate for people experiencing occasional sleeplessness‚ those with jet lag or those wanting to promote sound‚ quality sleep. These positive findings are most likely mediated through Melatonin’s involvement with membrane-bound receptors located in the suprachismatic nucleus‚ the pars tuberalis‚ and other brain regions.
The pineal gland is the organ where information about light and dark is processed and then relayed to cells throughout the body. The eyes deliver information to the pineal gland through different routes that include the retinohypothalamic tract and the suprachiasmatic nuclei. Norepinephrine released from postganglionic nerve endings to the pineal gland helps control melatonin release. This release of norepinephrine to the pinealocytes occurs at night‚ which is when melatonin secretion and levels throughout the body begin to rise.
Melatonin‚ due to its considerable lipophilicity‚ is able to cross any cell membrane and enter any tissue or cellular compartment. Therefore it is likely that some of melatonin's biochemical effects are elicited through intracellular binding sites in addition to its interactions with membrane-bound receptors (Hardeland‚ 95). Melatonin's high lipophilicity is what allows it to transmit the signal of darkness to every cell in the body‚ in turn acting as the eyes for each cell‚ organ and tissue. This is why melatonin levels throughout the body are so important for promoting calm‚ restful sleep and a relaxed mood in the evening by supporting natural circadian rhythms.
In addition to its effects on sleep‚ Melatonin is believed to play a major role in the biological termination of free-radical induced redox reactions. Melatonin is reported to have a large capacity to trap hydroxyl radicals‚ the free radical species with the highest relative reactivity. Melatonin also efficiently traps peroxyl radicals and superoxide anions. Melatonin participates in a two-step process in which it first interacts with a hydroxyl or peroxyl radial to give a melatonyl cation radical‚ which then combines with a superoxide anion to neutralize the electrical charges and pairing electrons.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Serving Size: 1 Capsule
Amount Per Serving / % DV
Melatonin 10mg / **
**Daily Value not established.
Other Ingredients: Rice flour‚ gelatin. Contains <2% of silica‚ vegetable magnesium stearate.
For adults‚ take one (1) capsule at bedtime as Melatonin may produce drowsiness. As a reminder‚ discuss the supplements and medications you take with your healthcare providers.
Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition‚ consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Do not drive‚ operate machinery or consume alcohol when taking this product. Limit use to two months with a break of one week. Not intended for use by persons under the age of 18. Keep out of reach of children. Do not use if seal under cap is broken or missing. Store at room temperature and avoid excessive heat.
PureFormulas is your one-stop shop for health supplements, vitamins, minerals and other nutritional supplements. We carry thousands of products from a huge variety of prescreened manufacturers because our goal is to help you achieve optimal health, regardless of your age, lifestyle or location.
At PureFormulas, we hand pick every item in our inventory. We only work with the most reputable, trusted manufacturers of vitamins, minerals and nutritional supplements.
When you order from PureFormulas, you're getting access to our large inventory, the convenience of fast, free shipping, and the comfort of knowing your order is guaranteed authentic and fresh. Our dedicated team is here to make sure you have access to the best health supplements, vitamins and minerals and other nutritional supplements. Our friendly, efficient customer service is second-to-none, and we guarantee your satisfaction on every order you place through PureFormulas.
We invite you to browse our large selection of vitamins and minerals, nutritional supplements and other health supplements, and please contact us if you have any questions. We look forward to meeting your needs today!
Domestic orders placed by 5 PM Eastern Time will be packed and shipped the same day, pending verification of billing information and the shipping method selected. Orders containing out-of-stock items or refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
Excludes all orders placed during weekends and on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year’s Day).