L-5-MTHF 120 Vegetarian Capsules

  • Item Number: DES1276
  • Serving Size: 1 Vegetarian Capsule(s)
  • Servings per Container: 120
  • Amount per Container: 120 Vegetarian Capsules
  • Price per Serving: $0.29
  • Price per Unit*: $0.29
  • * Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
  Free Shipping included for all US addresses and territories View Details
  • Availability: 18 In Stock
  • This item will ship on Monday before 5PM EST.

  • MFG # MTH120
  • UPC # 879452002784
  • L-5-MTHF was designed for patients with demonstrated increased need for folate such as those with either the A1298C or C677T MTHFR mutation. It provides 1000 mcg per capsule of folate in the bioidentical‚ bioactive form‚ 5-MethylTetraHydroFolate. L-5-MTHF (the "L" signifying that it is the all-natural [6S] isomer) is the active circulating form of folate found in the body and one of the several forms found in food. In nature it is found only as this [6S] isomer‚ which is why DFH provides 5-MTHF as this natural isomer rather than the mixed (or racemic) form.

    Individuals who have tested homozygous with either the A1298C or C677T MTHFR mutation‚ or those with elevated homocysteine levels‚ should be using L-5-MTHF as the preferred form of folate supplementation. This will be more effective for them than other forms of folic acid or folates.

    Others who may benefit from L-5-MTHF:

    1) Pregnant women and women wishing to become pregnant who have familial history of depression‚ high homocysteine levels‚ or genetic defect in MTHFR. Note: All pregnant women should takePrenatal Pro™ as their
    comprehensive multivitamin; can combine with L-5-MTHF if higher levels of folate are needed.
    2) Women with abnormal pap smears (precancerous)
    3) Those with very high homocysteine levels not responding quickly to Homocysteine Supreme™(consider using them together)
    4) Dialysis patients
    5) Organic acid testing that reveals elevated FIGLU (marker used to identify folate deficiency)
    6) Patients with family history of dementia/vascular dementia
    7) Patients with depression
    8) Long-term alcoholism
    9) Long-term use of oral contraceptives‚ and

    persistent use of medications to lower folate levels‚ including high doses of NSAIDs such as aspirin or ibuprofen; anticonvulsants (phenytoin‚ phenobarbital‚ and primidone); trimethoprim (antibiotic)‚ pyrimethamine (antimalarial)‚ triamterene (blood pressure med.) and sulfasalazine (treatment for ulcerative colitis).

    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Official Website: http://www.designsforhealth.com

Serving Size: 1 Capsule

Amount Per Serving / % DV

Folate (as [6S]-5-Methyltetrahydrofolate) 1000mcg / 250%

*Daily Value not established.

Other Ingredients:
Microcrystalline cellulose‚ spinach juice powder‚ L-leucine.

Does not contain gluten.

As a dietary supplement‚ take one capsule daily or as directed by your health care practitioner.

Store in a cool‚ dry place.
Keep out of reach of children.

  • GMP Certification
  • Gluten Free
  • Vegetarian Product
  • Certificate of Analysis
  • Made In The Usa

Ratings & Reviews

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Overall Rating for L-5-MTHF 120 Vegetarian Capsules

Based on 5 reviews

Displaying reviews 1-5 of 5

  • By Heather Bryse-Harvey
    from United States



    Great Product - no potato

    My Naturopath prescribed this for me to help with my Factor 5 Leiden issues. I also have a sensitivity to potato and many capsules apparently contain Potato (who knew?) so this one is safe! This company is always fast and the product always good. I recommend them.

    I would recommend this item to a friend.

  • By Sridevi
    from Ashburn, VA



    Proper Folate

    My physician recommended L-5-MTHF to me. Why? Its a proper bio-available form of Folate. Its working for me.


      Easy to swallow


    I would recommend this item to a friend.

  • By kunzang
    from Berkeley, ca



    proper folate

    My physician (who is also certified in functional/integrative medicine )recommended I take L-5-MTHF : L-5-MTHF. Why? Its a proper bio-available form of Folate (rather than the rather useless yet ubiquitous folic acid"). Designs for Health is the only one I found out there which markets such a product. Pureformulas has a decent price plus NO shipping.

    I would recommend this item to a friend.

  • By Aaron
    from Oregon



    MTHFR Supplement

    L-5-MTHF not bad but the dose is far to low to be effective. I use other products with a higher dose and better quality. To be effective you need atleast 5mg to 10mg of MTHFR a day. Which means you would need to take 10 pills a day - ouch !




      not enough strength hard to take costly doesnt work
  • By Olivia
    from Chicago, Illinois



    Excellent if you have MTHFR or even othe

    I have been tested and have MTHFR with C677T I believe my husband also has a mutation too. Fortunately our son was born healthy due to the fact I was taking extra folate on my own as a precaution although I didnt know about the mutation at the time. My husband and I take L-5-MTHF by Designs for Health and have found a dramatic increase in attention span the ability to stay focused for long periods of time and the ability to concentrate. Our energy levels have improved too. It has removed our brain fog. We also give our son a little of this in his food maybe a third of the pill or so a day or every other day depending and find that it dramatically improved his speech and verbal abilities very very quickly. Hes 2 years old. My husband and I also take NOW brand B6 and Mercolas sublingual B12 along with a multi that does not contain folic acid. I have read that if you take synthetic folic acid it will more easily bind to your receptor sites and tie them up (uselessly since its not useable) while the useable folic acid will remain unused. Our son eats liver now and then too along with his multi. Im not a doctor these are just my experiences. Our family really likes L-5-MTHF and are grateful that its available. We even recommended it to our parents and they have had similar benefits.


      Easy to swallow Works great Saw benefits quickly Can easily open capsule to give my son a smaller dose No aftertaste No tummy troubles even on empty stomach


      I only wish it was made of organic spinich I would even be willing to pay more for it

    I would recommend this item to a friend.


Displaying reviews 1-5 of 5

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