Glucosamine Chondroitin MSM 120 Capsules

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  • Brand: Doctors Best
  • Item Number: DRB1118
  • Serving Size: 2 Capsule(s)
  • Servings per Container: 60
  • Amount per Container: 120 Capsules
  • Price per Serving: $0.24
  • Price per Unit*: $0.12
  • * Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Regular Price: $25.99 $14.59
 
  • Availability: 11 In Stock
  • This item will ship the next business day before 5PM EST

 
  • MFG # DRB-00080
  • UPC # 753950000803
  • Science-based nutrition
    Dietary supplement
    Maintains healthy joints and connective tissue

    Contains sodium-free potassium stabilized glucosamine sulfate‚ bovine chondroitin sulfate and pure MSM. (OptiMSM®).

    Benefits:

    Supports Joint Structure‚ Function‚ and Comfort

    The Roles of Glucosamine and Chondroitin Sulfate in Joints
    Articular cartilage is a connective tissue composed of specialized cells (chondrocytes) embedded in a matrix of protein fibers (mostly collagen) and clusters of complex proteoglycan molecules that consist of a protein core with numerous side chains. These side chains‚ chiefly chondroitin sulfate and keratin sulfate‚ are long polysaccharide molecules called glycosaminoglycans. Chondroitin sulfate (CS) and the other glycosaminoglycans strongly attract water due to the negative charges of their sulfate groups. These negative charges also repel each other‚ creating spaces between glycosaminoglycan side chains where water can enter. This combination of solid and liquid gives cartilage a compressible quality that allows it to function as a shock absorber for joints.

    Glucosamine is a fundamental building block for proteoglycans and glycosaminoglycans. Glucosamine sulfate (GS) helps to maintain joint health through its ability to both act as a component of and stimulate formation of cartilage glycosaminoglycans and the hyaluronic acid backbone essential for the formation of cartilage proteoglycans.

    The Abundant Evidence Behind Glucosamine and Chondroitin Sulfate
    Extensive joint health research over the past few decades has investigated the effects of glucosamine sulfate‚ chondroitin sulfate‚ or a combination of the two. A 2009 meta-analysis summarized results from 6 well-designed studies involving a total of 1‚502 research participants. The authors of this meta-analysis were able to make some conclusions about the apparent effectiveness of long-term oral supplementation with CS or GS. Glucosamine sulfate at 1‚500 mg daily over a period of at least 3 years and chondroitin sulfate at 800 mg daily over a period of at least 2 years both helped subjects maintain healthy knee cartilage structure.3 In a 2008 review of GS & CS used for joint support‚ the London physician who wrote it concludes that‚ “Glucosamine‚ chondroitin‚ and the combination of these two agents have stood the test of time.”

    Glucosamine sulfate is one of the most important—and thoroughly researched—dietary supplements for joint health ever developed. In addition to its potential to influence joint structure (and thus function)‚ research also backs the ability of GS to influence joint comfort. In one such multicenter‚ randomized‚ double-blind‚ parallel-group study of 252 subjects‚ joint comfort in the knee was found to be higher in the glucosamine sulfate group than the placebo group.6 Similar studies of equal magnitude found that GS enhanced joint comfort. Key among findings from these types of studies is the reoccurring theme of a good safety profile for glucosamine sulfate; reported “side effects” of GS were essentially no different than placebo.

    Similar to glucosamine‚ chondroitin sulfate is known to influence the maintenance of healthy cartilage—in this case by acting on matrix metalloproteases (MMPs). Chondroitin sulfate has been shown to inhibit MMP-3 synthesis‚ which plays an important role in homeostasis of cartilage proteoglycans. Additionally‚ CS can downplay MMP-13 in chondrocytes‚ helping to maintain the integrity of articular cartilage matrix.

    Clinical Trials Explore MSM’s Joint Action
    Results from a randomized‚ double-blind‚ placebo-controlled pilot trial examining the effect of MSM supplementation on joint comfort in 50 men and women are promising. Subjects taking OptiMSM® methylsulfonylmethane for 12 weeks experienced greater joint comfort than those taking placebo‚ suggesting potential for MSM as a joint support nutrient that warrants further investigation in larger clinical trials. MSM also produced statistically significant changes in urinary malondialdehyde‚ a marker of oxidative stress.

    MSM has also been used in combination with glucosamine to study their impact on the health of joints. In one such study‚ a total of 118 subjects were randomized into one of four groups for 12 weeks: glucosamine (500 mg three times daily)‚ MSM (500 mg three times daily)‚ the combination of glucosamine and MSM‚ or a placebo treatment. Glucosamine alone and MSM alone were shown to enhance joint function‚ while the combination was found to be even more effective‚ by both subjective and objective measurements.



    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Official Website: http://www.drbvitamins.com

Serving Size: 2 Capsules
Serving per container: 60 servings

Amount Per Serving % DV

Chloride (from glucosamine sulfate 2KCl) 84 mg 2%
Sodium (from chondroitin sulfate) 28 mg 1%
Potassium (from glucosamine sulfate 2KCl) 91 mg 3%
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Glucosamine sulfate 2KCl 750 mg †
Chondroitin sulfate 600 mg †
(from chondroitin sulfate sodium)
Methylsulfonylmethane 500 mg †
OptiMSM®
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* Percent Daily Values based on a diet supplying 2000 calories per day.
† Daily Value not established.

Other ingredients: Cellulose‚ magnesium stearate (vegetable source)‚ gelatin (capsule).

Note: Glucosamine is obtained from the shells of shellfish. Contains sodium-free potassium stabilized glucosamine sulfate‚ bovine chondroitin sulfate plus pure MSM (OptiMSM®).

Contains nothing other than listed ingredients.

Does Not Contain: milk‚ egg‚ wheat‚ gluten‚ corn‚ soy‚ sugar‚ sweeteners‚ starch‚ salt‚ or preservatives.

Take 2 capsules twice daily‚ with or without food.

Glucosamine is obtained from the shells of shellfish.

  • GMP Certification
  • Heavy Metals Free
  • Made In The Usa
  • Milk Free
  • Egg Free
  • Wheat Free
  • Gluten Free
  • Corn Free
  • Soy Free
  • Sugar Free
  • Starch Free
  • Preservative Free

Ratings & Reviews

Review This Item

Overall Rating for Glucosamine Chondroitin MSM 120 Capsules

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4 7 Based on 7 reviews

Displaying reviews 1-7 of 7

  • By
    from Greenwich, CT

      5
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    5/26/2014

    Used this product before and liked it so

    Good product. Easily consumed. Useful combination of supplements.

    Pros

      Easy consumption

    Cons

    I would recommend this item to a friend.

     
  • By
    from Here

      4
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    3/25/2014

    Affordable and so good for... my neck!

    I take 2 of these every day and my neck and shoulder pain is ancient history. Actually theyre so well-priced I give them to my dog too (a reduced dosage approved by my vet). Hes 12 years old and getting on... and so am I... :) Thanks PureFormulas for right-price products and the fastest (free!) delivery times on Planet Earth!

    I would recommend this item to a friend.

     
  • By
    from Lacey. Wa

      5
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    8/23/2013

    My docter told me this brand is just gre

    I have re-ordered Glucosamine Chondroitin MSM 3 times. The doctor said capsules are more easily assimilated than tablets. And in addition to the already low price there is an extra 15% off on doctors best products.

    Pros

      price and quality

    Cons

      nothing

    I would recommend this item to a friend.

     
  • By
    from Georgia

      5
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    4/08/2013

    Great if you work out

    Glucosamine Chondroitin MSM is a necessity if you exercise often to help repair your joints/ligaments.

    I would recommend this item to a friend.

     
  • By
    from Crown Point, IN 46307

      5
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    3/02/2013

    GLUCOSAMINE CHONDROITIN MSM

    MY HUSBAND AND ME BOTH TAKE THIS PRODUCT FOR ARTHRITIS AND IT WORKS!

    Pros

      TAKES THE PAIN AWAY AND IS SAFE FOR THE BODY! ALSO THE PRICE IS RIGHT & SHIPPING AND HANDLING AND TAX IS FREE......WHAT A BONUS!!!

    Cons

      NOTHING I REALLY DISLIKE ABOUT THIS PRODUCT...VERY GOOD PRODUCT...

    I would recommend this item to a friend.

     
  • By
    from elk river, MN

      3
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    12/04/2012

    Too early to tell

    I have arthritis in my hands and have started again on Glucosamine Chondroitin MSM. I think it is better but not sure quite yet. As far as service you guys are great! Overall everything is good except I wish we knew how much we should be taking for different ailments etc.

    I would recommend this item to a friend.

     
  • By
    from Eugene, OR

      4
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    11/15/2012

    works great for joint discomfort.

    Naturpathic dr prescribed and I have been using them for 2-3 years. Joints feel better.

    I would recommend this item to a friend.

     

Displaying reviews 1-7 of 7

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