|MFG # 240|
UPC # 812806102402
Official Website: http://www.bio-genesis.com
DIETARY SUPPLEMENTATION MAY SUPPORT HEALTHY PRODUCTION AND REGULATION OF ANDROGENS, ESTROGENS, CORTISOL
- May enhance feelings of well-being
- May protect against cardiovascular disease dysfunction
- May support a healthy libido
- May promote maintenance of healthy bone density
DHEA (or dehydroepiandrosterone) is a hormone produced by the adrenal gland and brain which serves as a precursor for all steroidal hormone production including both testosterone and estrogens. It is the body’s most abundant circulating steroid hormone, though the levels are generally higher in men than in women. Research has shown that levels peak at age 25 and markedly decline from there, with a decline of over 80% by age 70.
ANTI-AGING: Low DHEA levels have been shown to be associated with decreased feelings of well-being, increased frailty, and increased mortality. A study involving 254 men and women between the ages of 65 and 70 measured levels of DHEA-s at baseline and 10 years later. Lower levels of baseline DHEA-s were significantly correlated with increased odds of frailty (or vulnerability to disease) 10 years later.
Ninety-nine women in their seventies were given DHEA or placebo for six months along with an exercise program. The women taking DHEA were found to significantly increase their lower body strength and function as compared to the placebo group.
CARDIOVASCULAR HEALTH: DHEA research shows that this hormone may help support cardiovascular health. The Massachusetts Male Aging study reported that men ages 40-70 with higher levels of DHEA-s were less likely to have heart disease when confounders such as age, smoking status, and alcohol intake were controlled. The research suggests that endothelial health increases with higher levels of DHEA-s. Endothelial health is central to cardiovascular health as an increase in stiffness can lead to increases in blood pressure and arterial plaque accumulation.
BONE HEALTH: DHEA may alter bone mineral density through mechanisms related to mineral absorption and metabolism and through inflammatory processes. DHEA helps to stimulate production of insulin-like growth factor 1 (IGF-1), which is high in young people and helps maintain new bone formation. A study of women aged 50-78 years who had osteoporosis due to long-term (at least three years) prednisone sage showed that, in comparison to calcium, vitamin D3 and oral thiazide diuretic, DHEA significantly increased bone osteocalcin (a calcium-binding protein), serum IGF-1, and bone mineral density in the lumbar spine and femoral neck.
SEXUAL HEALTH: Libido has been shown to decrease with age, particularly in women. Healthy, postmenopausal women ages 50-60 were given either 10 mg DHEA, oral estradiol, oral tibolone, or a vitamin D placebo for one year. Those given DHEA were found to have significantly improved sexual function and frequency of sexual intercourse. Another study of 138 women in differing stages of menopause found that the best model for predicting sexual function during postmenopause were the levels of DHEA-s and estradiol; the lower the level of DHEA-s, the more likely to have a sexual dysfunction.
INSULIN SENSITIVITY: Research is beginning to elucidate the mechanism for how DHEA may increase insulin sensitivity. DHEA supplementation was shown to increase the number and size of insulin-secreting cells in the pancreas of rats. Human trials have shown promising results as well with subjects who had below normal levels of DHEA receiving either DHEA supplementation or a placebo. The DHEA-supplemented group required significantly higher amounts of glucose to raise their blood sugar level.
DHEA TR is specifically formulated so that clinicians can prescribe a low amount of DHEA, and increase in small increments as necessary. The fiber-based time-release system allows the product to provide a stable amount of DHEA from which the body can use what it needs, thus avoiding cortisol surges or fluctuations in levels of androgens and estrogens. The time-release lasts anywhere from 6-12 hours, depending on transit time and digestive capabilities, and this allows for a normal circadian rhythm of both DHEA and cortisol. This should be dosed in the morning, as this is the when the adrenal glands usually release DHEA.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.