Domestic orders placed by 5 PM Eastern Time will be packed and shipped the
same day, pending verification of billing information and the shipping
Orders containing refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
If an item on your order is on backorder we will notify you by email
and we will ship what we have in stock, the backordered item (s) will be
shipped as soon as it is back in stock (usually within 1 week or less)
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Order before 5 p.m. EST and this item will ship out today. Except during weekends and holidays.
We’re fast like that. Place your order before 5 p.m. and it will ship the same day, as long as we can verify billing and shipping information. Refrigerated items will be processed quickly, but might not ship the same day.
If it’s backordered, we’ll notify you by email and will ship it when it’s available (usually 1 week or less).
Co-Enzyme Q10 softgels‚ provided by Douglas Laboratories‚ contain pure co-enzyme Q10 (ubiquinone). Co-enzyme Q10 is solubilized in a base of rice bran oil and vitamin E to enhance absorption of co-enzyme Q10.
Co-Enzyme Q10 softgels may be a useful dietary supplement for those who wish to support their body’s own production of co-enzyme Q10.
Co-Enzyme Q10 (ubiquinone) is an important ratelimiting cofactor in the mitochondrial electron transport chain‚ the biochemical pathway in cellular respiration from which adenosine triphosphate (ATP)‚ the form of energy used by the body‚ is derived. Since cellular activities are dependent upon energy‚ co-enzyme Q10 is crucial for the efficient functioning of nearly every cell. In addition to its well-established function as a component of the mitochondrial electron transport chain‚ co-enzyme Q10 has in recent years acquired increasing attention regarding its antioxidant properties. Co-Enzyme Q10 occurs in all cellular membranes as well as in blood serum and in serum lipoproteins.
As a lipid-soluble antioxidant‚ coenzyme Q10 efficiently protects membrane phospholipids and serum low-density lipoproteins from lipid peroxidation. And‚ as recent data indicate‚ it also protects mitochondrial membrane proteins and DNA from free radical induced oxidative damage. These effects of co-enzyme Q10 are independent of those of other antioxidants‚ such as vitamin E; although co-enzyme Q10 can also extend the functions of vitamin E by regenerating it from its oxidized form.
Tissue co-enzyme Q10 levels are regulated through the mevalonate pathway‚ increasing with various forms of oxidative stress‚ and decreasing during aging. Related to its antioxidant properties‚ co-enzyme Q10 is important for normal immune function. This has been shown in a number of experimental and clinical studies. Healthy people have the ability to synthesize adequate amounts of co-enzyme Q10. According to Dr. Karl Folkers and other researchers‚ humans can synthesize co-enzyme Q10 from the amino acids tyrosine or phenylalanine and mevalonic acid‚ all of which are abundant in the body.
However‚ the synthesis is a complex process involving 15 separate steps which require many enzymes‚ nutritional mineral cofactors‚ and vitamin coenzymes. As a result‚ the biosynthesis of co-enzyme Q10 in the human body requires a good diet – one that is high in vitamins‚ minerals‚ and other nutrient factors. Yet‚ it has been shown by NHANES I and II studies that many Americans do not consume an adequate diet. Rather‚ for many‚ dietary intake of water soluble vitamins‚ vitamin A‚ and some minerals and trace elements is insufficient. Many of these nutrients are essential for the biosynthesis of co-enzyme Q10.
Thus‚ it is not surprising that the nutritional status of co-enzyme Q10 tends to decline with advancing age. In addition‚ it has been shown that in disease states‚ nutrients from food sources may not be readily absorbed or bioavailable. According to Folkers and other experts‚ co-enzyme Q10 should be considered an essential nutrient‚ as it is well established that coenzyme Q10 is essential for the health of every cell in the human body.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Amount Per Serving
Vitamin A ...2‚000 IU / 40% DV (as Natural Beta Carotene from D. Salina)
Vitamin E ...100 IU / 333% DV (a d-alpha tocopherol with mixed tocopherols)
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When you order from PureFormulas, you're getting access to our large inventory, the convenience of fast, free shipping, and the comfort of knowing your order is guaranteed authentic and fresh. Our dedicated team is here to make sure you have access to the best health supplements, vitamins and minerals and other nutritional supplements. Our friendly, efficient customer service is second-to-none, and we guarantee your satisfaction on every order you place through PureFormulas.
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Domestic orders placed by 5 PM Eastern Time will be packed and shipped the same day, pending verification of billing information and the shipping method selected. Orders containing out-of-stock items or refrigerated items will be processed as quickly as possible, but won't necessarily be shipped out the same day.
Excludes all orders placed during weekends and on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year’s Day).