CLA Tonalin 1300 mg 60 Softgels
Item # PH1042
Our Price: $30.50
Free Shipping Included for all US addresses and territories
Product Q & A
|MFG # 50274|
UPC # 716963502740
Official Website: http://www.physiologics.com
Scientifically Formulated to Support a Healthy Body Composition
Laboratory Tested To Guarantee Quality
For Health Care Professional Use Only
HOW PATIENTS MAY BENEFIT
Use with a reduced calorie diet and regular exercise program Helps support metabolism of dietary lipids, carbohydrates, and proteins for patients with diverse eating patterns and meal compositions
PhysioLogics Tonalin® CLA provides multi-level diet support by working through distinct enzymatic and metabolic pathways. The patented, active ingredients have been used in a variety of in-vivo human trials. This product has been scientifically formulated to help support a healthy body composition. Use with a reduced calorie diet and regular exercise program.
STRUCTURE AND FUNCTION
PhysioLogics Tonalin® CLA contains Conjugated Linoleic Acid (CLA), which exists as several isomers of the essential polyunsaturated fatty acid Linoleic Acid. Bioactive isomers include the cis-9, trans-11 isomer and trans-10, cis-12 isomer. Stereoisomers have seemingly different biological effects, making a precise mechanism of action difficult to discern. CLA has been shown to promote certain enzymes responsible for fatty acid betaoxidation and mobilization, such as hormone sensitive lipoprotein lipase. Preliminary evidence suggests that CLA promotes activation of peroxisome proliferatoractivated receptor alpha (PPARa), a regulator of lipid homeostasis. Other mechanisms discussed in the scientific literature include CLA's positive effects on total carnitine palmitoyl-transferase activity, promoting fatty acyl CoA transfer from the cytosol into the mitochondrial matrix. Uncoupling protein gene expression, as evidenced in murine models, may also be partially responsible for the metabolic effects of CLA at the level of ATP formation.
In a double-blinded trial, 60 male and female subjects who met the inclusion criteria of BMI>25 were randomized to receive one of four doses of Tonalin® CLA or matching placebo. Statistical analysis using Dunnett's test to make pair-wise comparisons of CLA vs. placebo revealed significant differences in body composition even at the lowest dose of 1.7g CLA per day. (Blankson et al, 2000) A double-blinded trial randomized 20 males and females to receive placebo or 1.8g per day of CLA from Tonalin®. Body composition was found to be significantly improved at 4, 8, and 12 week measures within CLA subjects and as compared to placebo subjects. (Thom et al, 2001)
PhysioLogics Tonalin® CLA contains scientifically tested ingredients for helping to inhibit triglyceride accumulation within adipocyte cells while simultaneously supporting metabolism of all of the major macronutrients. Studies show that CLA can help support a healthy body composition. Use with a reduced calorie diet and regular exercise program.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
|Amount Per Serving|
Calories from Fat ...10
Total Fat ...1g / 2% DV**
Polyunsaturated Fat ...1g***
CLA ...1,000mg (1g)***
(from 1,250 mg of Tonalin®)
Contains 78-84% Conjugated Linoleic Acid (CLA)
**Percent Daily Values are based on a 2,000 calorie diet.
***Daily Value not established.
Other Ingredients: Gelatin, Glycerin, Caramel Color.
FREE OF: yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, soy,
artificial color, artificial flavor, sodium.
Allergy Information - Product Details
- No Artificial Flavors
- Gluten Free
- Preservatives Free
- Salt/Sodium Free
- Soy Free
- Wheat Free
- Yeast Free
|For adults, take one (1) softgel twice daily, preferably with a meal or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you take with your health care providers.|
|Do not use if seal under cap is broken or missing.|
KEEP OUT OF REACH OF CHILDREN.
Store in a dry place and avoid excessive heat.
If you are pregnant, nursing or taking any medications, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur.
Overall Rating for CLA Tonalin 1300 mg 60 Softgels