Best MSM 1500 mg 120 Tablets

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  • Brand: Doctors Best
  • Item Number: DRB1088
  • Serving Size: 1 Tablet
  • Servings per Container: 120
  • Amount per Container: 120 Tablets
  • Price per Serving: $0.07
  Free Shipping included for all US addresses and territories View Details
Regular Price: $14.99 $8.37
 
  • Availability: 19 In Stock
  • This item will ship today if ordered within 3 hr 1 min
 
  • MFG # DRB-00097
  • UPC # 753950000971
  • Best MSM 1500 mg supplies highly purified MSM (methylsulfonylmethane)‚ a compound notable for its methyl groups (required for numerous metabolic functions) and the conditionally essential mineral sulfur‚ which is a crucial component of powerful antioxidants such as N-acetylcysteine and glutathione. Although MSM occurs naturally in some foods and in the human body at low concentrations‚ a significant amount of MSM is lost during the heating and processing of foods.

    Features:
    -Science-based nutrition
    -Dietary supplement
    -Promotes joint comfort and mobility
    -Supports healthy immune response
    -Enhances antioxidant defenses

    Promotes joint comfort and mobility

    In a double blind‚ placebo-controlled trial‚ 50 men and women were randomized to receive either 3‚375 mg (3.375 grams) of MSM or a placebo daily for 12 weeks. Participants were instructed to take the tablets (each was 1.125 grams) in three doses per day with food‚ and to avoid taking the tablets before bed. Several validated and reliable scoring methods were used to measure joint function and comfort during the study. Compared with placebo‚ MSM was shown to significantly promote joint function and comfort‚ without side effects.

    A larger dose was used in a randomized‚ double blind‚ placebo-controlled trial of 50 men and women (ages 40–76).8 Participants were randomized into two groups to receive either placebo capsules or OptiMSM® in 1 gram capsules for 12 weeks. They were instructed to ramp up to the eventual dose of 6 grams per day by starting with two doses of 2 grams per day for 3 days‚ followed by an increase to 4 grams per day for the next 4 days. At the beginning of the second week‚ the dose was raised to 3 grams twice daily. Participants were instructed to take the MSM with food‚ and to avoid taking it at bedtime. Knee joint function and comfort were measured by standardized (reliable and valid) questionnaires. After 12 weeks‚ physical function and knee joint comfort were shown to be superior in the MSM group when compared to placebo.

    In a more complex double blind study‚ MSM was tested versus (a) a placebo‚ (b) glucosamine‚ and (c) a combination of MSM with glucosamine‚ in 118 men and women (ages 40–70).9 Participants were randomized into four groups to receive either a placebo‚ MSM alone (500 mg three times daily)‚ glucosamine alone (500 mg three times daily)‚ or MSM + glucosamine (500 mg each‚ three times daily). Using a number of analytical tools that measured joint functionality‚ comfort‚ and quality of life related to joint health‚ the researchers found that the MSM and glucosamine groups experienced significant support for joint health‚ whereas the placebo group experienced no such benefits. Additionally‚ the combination of MSM + glucosamine was significantly better at promoting joint comfort and functional ability than either taken alone.

    MSM could serve as a source of sulfur to support the maintenance and formation of cartilage‚ thereby supporting knee joint health.10 Its two methyl groups could be valuable to its actions‚ being necessary for tissue repair and maintenance. Its molecular structure suggests it could also have redox (electronic catalytic) properties that would facilitate antioxidant or other human benefits.

    Enhances antioxidant defenses

    Supports healthy immune response

    Oxidative stress is a term used to describe negative imbalance between production of reactive oxygen species (ROS) and the body’s antioxidant capacities. Strenuous exercise have the potential to create an uptick of ROS‚ and subsequently oxidative stress. Human and animal studies suggest that taking MSM prior to exercise may help to ease oxidative stress‚ especially in individuals not accustomed to the stress of exercise.

    In an exploratory trial of eight healthy men accustomed to a moderate amount of exercise (no more than 2.5 hours per week)‚ the effect of MSM on antioxidant capacity after exercise was investigated. Half of the participants were given 1.5 grams of OptiMSM® per day‚ and the other half 3.0 grams per day. Both groups took the MSM for 30 days‚ and were instructed to split their daily dose in order to take half of it in the morning and half in the evening. On two exercise test days (before and after 28 days of MSM consumption)‚ participants took their morning MSM dose immediately prior to eating a standardized breakfast‚ then performed 18 sets of a standardized exercise. A statistically significant increase in blood antioxidant capacity following exercise was reported in the group taking 3 grams MSM daily‚ as measured by the well-accepted Trolox Equivalent Antioxidant Capacity assay.

    MSM has been suggested to support healthy immune function through antioxidant actions. Neutrophils‚ the most abundant white blood cells in the body‚ routinely release free radicals crucial to their immune activities; this can be a double-edged sword‚ as excessive free radical generation contributes to oxidative stress. Laboratory research suggests MSM can help regulate free radical production by neutrophils. In mice macrophage (immune) cells‚ MSM was shown to down-regulate overactive immune factors without being toxic to the cells. In a mouse model examining joint health‚ MSM dissolved in the drinking water influenced immune function in a way that significantly supported joint structure and function when compared to mice in a control group.

    MSM’s benefits for human immune function were studied in an open-label clinical trial. A total 50 men and women were given OptiMSM®‚ 2.6 grams per day for 30 days.17 The MSM was given as four 650 mg capsules—two in the morning and two in the afternoon—each day. Immune function was measured by questionnaire‚ which included three subsections of questions about upper respiratory health (the head‚ eyes‚ nose‚ and throat)‚ lower respiratory health (the lungs and chest)‚ and energy level. The data suggested MSM produced clinically significant support for the upper respiratory system after one week‚ the lower respiratory system after three weeks‚ and enhanced energy levels after two weeks. These benefits continued into the fourth and final week of the study. A subset of 16 participants who experienced the least benefit from the MSM were selected to continue taking OptiMSM® for an additional 14 days‚ but at the higher dose of 5.2 grams per day. These individuals then reported experiencing significantly enhanced energy levels and superior overall respiratory scores.



    While new research is exploring the potential of methylsulfonylmethane in promoting the maintenance of GI health and bone health‚19 the current clinical evidence shows MSM provides meaningful support for the joints‚ for immune function‚ and for the body’s antioxidant and overall protective capacities. MSM is proven very safe to take‚ very well tolerated‚ and effective at intakes as high as 6000 mg (6 grams) per day.





    These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Official Website: http://www.drbvitamins.com

Serving Size: 1 Tablet
Serving per container: 120 servings

Amount Per Serving %DV

Methylsulfonylmethane 1.5 grams (1500 mg) †
OptiMSMl®
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† Daily Values Not Established.

Other Ingredients: Microcrystalline cellulose‚ stearic acid‚ magnesium stearate (vegetable source).

Contains nothing other than listed ingredients.

As a dietary supplement‚ take 1 to 2 tablets daily‚ with or without food.

Effective dosages for the various reported uses of MSM range from 500 mg to 6 grams per day. 1000 mg per day is recommended to restore normal MSM concentrations‚ while higher doses may be necessary for specific uses.

MSM is considered to be as non-toxic to the body as water and is‚ therefore‚ completely safe at the higher dosage levels.

  • GMP Certification
  • Made In The Usa
  • Gluten Free

Ratings & Reviews

Review This Item

Overall Rating for Best MSM 1500 mg 120 Tablets

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5 16 Based on 16 reviews

Displaying reviews 1-10 of 16

  • By
    from FL

      5
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    10/11/2014

    Great Product!

    Best MSM by Doctors Best helps my hair and joints.

    Pros

      Everything.

    Cons

      None.

    I would recommend this item to a friend.

     
  • By
    from Beitar

      5
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    9/28/2014

    Thanks!

    Best MSM by Doctors Best is exactly what the doctor ordered.

    Pros

      Everything.

    Cons

      Nothing.

    I would recommend this item to a friend.

     
  • By
    from VI

      5
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    5/04/2014

    It Works

    I take this for skin and nails and it works for that.

    Pros

      Easy to take Price

    Cons

      None

    I would recommend this item to a friend.

     
  • By
    from Alabama

      5
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    5/03/2014

    best deal/ it works!!

    This is the best deal I have found online for quality msm. Also This product definitely works and I have used it for hair growth/lengthening the anagen phase of the hair. Definitely purchase this if you are at all interested in inceasing hair growth. Another point this is the active key ingredient in Hairfinity hair vitamins.

    Pros

      Lengthens anagen phase/great price for the quality

    Cons

      None

    I would recommend this item to a friend.

     
  • By
    from Chicago, iL

      5
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    4/23/2014

    Great product

    This is a terrific deal- been using for several years

    Pros

    Cons

      Pills are huge

    I would recommend this item to a friend.

     
  • By
    from VA

      5
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    3/26/2014

    Great product

    I really like MSM it is a good product. Ive been taking it for awhile now.

    I would recommend this item to a friend.

     
  • By
    from Pakistan

      2
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    2/15/2014

    MSM 1500

    Hi Dear one of my friend needs this medicine (MSM 1500) in Pakistan advised by a Orthopedic specialist so how can we order this and what will be the total cost including shipping charges drop a mail to me. will be thankful to you. Regards

    I would recommend this item to a friend.

     
  • By
    from Asheville, NC

      5
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    11/08/2013

    Great product at a great price

    Best MSM was recommended by my familys doctor to help boost detox via the sulphur pathways. Weve been taking Best MSM for nearly a year.

    Pros

      Inexpensive Works well

    Cons

      Pills are quite large so difficult for kids to swallow

    I would recommend this item to a friend.

     
  • By
    from Scottsdale, AZ

      4
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    9/04/2013

    So far so good

    This is my first time trying Best MSM I read great feedback regarding Best MSM.

    Pros

      benefits

    Cons

      cost

    I would recommend this item to a friend.

     
  • By
    from Tennessee

      4
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    8/29/2013

    Lung Support

    I am taking Best MSM for my lungs. I have asthma and this is supposed to help support my lungs. I havent taken it long enough to tell how well it is working but I am feeling great. The quality of Best MSM is great.

    Pros

      Quality Value

    Cons

    I would recommend this item to a friend.

     

Displaying reviews 1-10 of 16

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